DEFICIÊNCIA DE VITAMINA B12 DEVIDO AO USO DE METFORMINA EM PACIENTES PORTADORES DE DIABETES MELLITUS TIPO 2
DOI:
https://doi.org/10.47820/recima21.v5i10.5724Palavras-chave:
Vitamina B12, Metformina, DiabetesResumo
O uso prolongado de metformina, tratamento comum para DM2, está associado à deficiência de vitamina B12, exigindo monitoramento regular dos níveis da vitamina em pacientes tratados. Material e Métodos: Trata-se de uma revisão integrativa da literatura sobre a deficiência de vitamina B12 induzida pela metformina em pacientes com diabetes tipo 2, utilizando artigos da PubMed de 2019 a 2024, com critérios rigorosos de inclusão e exclusão. Resultado e Discussão: A metformina está associada à deficiência de vitamina B12, impactando a absorção intestinal da vitamina, o que pode levar a complicações como neuropatia e anemia. Estudos mostram que o uso prolongado e em altas doses aumenta o risco de deficiência de B12 em pacientes com diabetes tipo 2. Conclusão: O uso de metformina está relacionado à deficiência de vitamina B12, afetando a absorção da vitamina e causando complicações como neuropatia e anemia em pacientes com diabetes tipo 2, especialmente em altas doses e tratamentos prolongados.
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