O USO DE CÉLULAS-TRONCO NA REGENERAÇÃO PERIODONTAL
DOI:
https://doi.org/10.47820/recima21.v5i12.6040Palavras-chave:
Periodontite, Regeneração, Células-troncoResumo
A periodontite é definida como uma doença infecto-inflamatória crônica associada a um biofilme disbiótico, levando ao desequilíbrio da homeostase, a perda dos tecidos de suporte periodontal e podendo culminar na perda dentária. A frequente presença de defeitos ósseos periodontais leva ao crescente interesse na odontologia pela regeneração periodontal, passando pela busca constante de novos biomateriais e, mais recentemente com a introdução de terapias baseadas em células-tronco. O objetivo desta revisão de literatura é analisar o potencial terapêutico das células tronco mesenquimais na regeneração periodontal, abordando os desafios associados à sua aplicação clínica. As células-tronco mesenquimais (CTMs), particularmente aquelas derivadas do ligamento periodontal, têm demonstrado potencial significativo na regeneração de tecidos periodontais danificados. Estudos indicam que essas células possuem a capacidade de diferenciação em vários tipos celulares, incluindo osteoblastos, cementoblastos e fibroblastos, essenciais para a formação de novo tecido periodontal.
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