USE OF ESMOLOL IN INTRAOPERATIVE AND POSTOPERATIVE NON-CARDIAC SURGERIES: An INTEGRATIVE REVIEW

Authors

DOI:

https://doi.org/10.47820/recima21.v2i10.770

Keywords:

Esmolol is a cardioselective antagonist of ultra short-acting

Abstract

Esmolol is a cardioselective antagonist of ultra short-acting ß1 receptor. It is effective in blunting responses to perioperative adrenergic stimuli, including tracheal intubation, intraoperative events caused by decreased anesthetic depth and tracheal extubation. Thus, it was the objective of this study to analyze in the national and international literature the effects of esmolol in the perioperative and postoperative period of noncardiac surgeries. This is an integrative review of literature carried out in the Virtual Health Library. The articles of the Latin American and Caribbean scientific and technical literature database (LILACS) and the Medical Literature Analysis and Retrieval System Online (MEDLINE) were selected. The results revealed that administration of esmolol brought benefits, not mentioning any malice with use, where in infusion this medication is more effective than bolus to control systolic blood pressure during endotracheal intubation and sternotomy, significantly reducing the need for anesthetic-analgesic, pain and incidence of NVP. Surveys also reported that esmolol had an opioid sparing effect in the intraoperative and immediate postoperative period in hypertensive patients undergoing laparoscopy. Esmolol in intravenous infusion reduced analgesic consumption both intraoperatively and postoperatively, reduced the visual analogue scale scores in the immediate postoperative period and extended the time for the first analgesia. Therefore, it was possible to verify that esmolol is a safe medication, with many advantages and with few adverse effects.

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Author Biographies

  • Helder Marques Lima Junior, FAHESP/IESVAP

    Médico formado pelo Instituto de Educação Superior do Vale do Parnaíba. Parnaíba – PI

  • Davi Sérgio dos Santos Pacífico, FAHESP/IESVAP

    Médico formado pelo Instituto de Educação Superior do Vale do Parnaíba. Parnaíba –PI

  • Edvaldo Pereira de Moura Filho, FAHESP/IESVAP

    Médico formado pelo Instituto de Educação Superior do Vale do Parnaíba. Parnaíba –PI

References

Celebi N, Cizmeci EA, Canbay O. Infusão intraoperatória de esmolol reduz o consumo pós-operatório de analgésicos e o uso de anestésico durante a septorrinoplastia: estudo randômico. Rev Bras Anestesiol. 2014;64(5):343-49.

Dereli N, Tutal ZB, Babayigit M, Kurtay A, Sahap M, Horasanli E. Efeito da infusão de esmolol sobre a necessidade de anestesia no intraoperatório e analgesia, náusea e vômito no pós-operatório em um grupo de pacientes submetidos à colecistectomia laparoscópica. Rev Bras Anestesiol. 2015;65(2):141-46

Çakirgoz MY, Efeito de diferentes doses de esmolol sobre a resposta hemodinâmica, BIS e resposta de movimento durante a intubação orotraqueal: estudo prospectivo, randômico e duplo‐cego. Brazilian Journal of Anesthesiology, 2014; 64(6): 425-32.

Efe EM, Bilgin BA, Alanoglu Z, Akbaba M, Denker M. Comparação de esmolol em bolus e infusão contínua na resposta hemodinâmica à laringoscopia, intubação orotraqueal e esternotomia em cirurgia de revascularização coronária. Brazilian Journal of Anesthesiology. 2014; 64(4): 247-52.

Gupta S, Tank P. A comparative study of efficacy and fentanyl for pressure attenuation during laryngoscopy and endotracheal intubation. Saudi J Anaesth. 2011;5:2-8.

Marconi MA, Lakatos EMª. Fundamentos de Metodologia Científica. 5ª reimpressão. São Paulo: Atlas, 2007.

Whitemore R, Knafl K The integrative review: updated methodology. Journal of Advanced Nursing. 2005; 52(5): 546–53.

Dereli N, Tutal ZB, Babayigit M, Kurtay A, Sahap M, Horasanli E. Efeito da infusão de esmolol sobre a necessidade de anestesia no intraoperatório e analgesia, náusea e vômito no pós-operatório em um grupo de pacientes submetidos à colecistectomia laparoscópica. Rev Bras Anestesiol. 2015;65(2):141-46.

Ozturk T, Kaya H, Aran G, Aksun M, Savaci S. Postoperative beneficial effects of esmolol in treated hypertensive patients undergoing laparoscopic cholecystectomy. Br. J Anaesth. 2008;100: 211-14.

Celebi N, Cizmeci EA, Canbay O. Infusão intraoperatória de esmolol reduz o consumo pós-operatório de analgésicos e o uso de anestésico durante a septorrinoplastia: estudo randômico. Rev Bras Anestesiol. 2014; 64(5):343-49.

Dogan SD, Ustun FE, Sener EB, Koksal E, Ustun YB, Kaya C, Ozkan F. Efeitos das infusões de lidocaína e esmolol sobre as alterações hemodinâmicas, necessidade de analgésicos e recuperação após colecistectomia laparoscópica. Rev. Bras. Anestesiol. 2016; 66(2): 145-50.

Collard V, Mistraletti G, Taqi A, et al. Intraoperative esmolol infusion in the absence of opioids spares postoperative fentanyl in patients undergoing ambulatory laparoscopic cholecystectomy. Anesth Analg. 2007;105: 1255-262.

Lahiri S, Sabyasachi D, Basu RS. Effect of intraoperative esmolol infusion on postoperative analgesia in laparoscopic cholecystectomy patients: a randomised controlled trial. Journal of Evolution of Med and Dent Sci. 2015; 4(81): 2278-4802.

Louizos Ant. A, Hadzilia SJ, Davilis DI; Samanta EG, Georgiou LG. Administration of esmolol in microlaryngeal surgery for blunting the hemodynamic response during laryngoscopy and tracheal intubation in cigarette smokers. Ann Otol Rhinol Laryngol; 116(2): 107-11, 2007.

Zhang XK; Hu Q; Chen, QH; Wang W X. The effect of continuous perfusion of esmolol on cardiovascular risk in elderly patients undergoing noncardiac surgery. Pharmazie. 2017; 72(8): 487-489.

Kim Y, Hwang W, Cho ML, Ela YM, Ahn S, Lee J. Surg Innov. Os efeitos da administração intra-operatória de esmolol sobre as respostas inflamatórias perioperatórias em pacientes submetidos à gastrectomia laparoscópica: um estudo dose-resposta. 2015; 22 (2): 177-82, 2015.

Published

28/10/2021

How to Cite

USE OF ESMOLOL IN INTRAOPERATIVE AND POSTOPERATIVE NON-CARDIAC SURGERIES: An INTEGRATIVE REVIEW . (2021). RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 2(10), e210770. https://doi.org/10.47820/recima21.v2i10.770