BIOACTIVE METABOLITES PRESENT IN A BOTTLE INDICATED FOR THE TREATMENT OF FEMALE INFERTILITY, PREPARED ACCORDING TO AN INTERNET RECIPE
DOI:
https://doi.org/10.47820/recima21.v5i4.5150Keywords:
Garrafadas. Female infertility. Phytotherapics. Folk medicineAbstract
Among the preparations made with medicinal plants, the "garrafada" is one of the most popular. It can be bought in popular stores or prepared at home. Although the use of garrafadas is a common practice in Brazil, there is no reference to such products in legislation. This research evaluated the recipe for a bottle indicated to treat female infertility, composed of pomegranate (Punica granatum L.), cat's claw (Uncaria tomentosa), yellow uxi (Endopleura uchi), clove (Syzygium aromaticum) and yam (Colocasia esculenta (L.) Schott). Initially, a literature search was carried out to see if these species contained metabolites with proven pharmacological activities related to the treatment of infertility. Extracts of each of the plant species and of all the species together in methanol and wine were then prepared by maceration to check for the presence of the chemical markers and to compare the efficiency of the extractions. The chemical composition of the systems was determined by analyzing the spectra obtained by ESI-MS.The results showed that the plant species have metabolites with pharmacological action related to the treatment of infertility. The methanol extracts had a higher number of metabolites than the extracts prepared in wine, corroborating the theory that the extraction system used in garrafadas is not the most efficient. The phytopharmaceuticals found in the garrafada, which have pharmacological actions related to the treatment of infertility, were isocoumarin bergenin, gallic acid and apeginin.
Downloads
References
ANIBAL, P. C. et al. Antifungal activity of the ethanolic extracts of Punica granatum L. and evaluation of the morphological and structural modifications of its compounds upon the cells of Candida ssp. Brazilian Journal of Microbiology, v. 44, n. 3, p. 839-848, 2013. DOI: https://doi.org/10.1590/S1517-83822013005000060
ANVISA - AGÊNCIA NACIONAL DE VIGILÂNCIA SANITÁRIA. Farmacopéia Brasileira. 6 ed. Brasilai; Anvisa, 2019. vol. 2.
ANWAR, M. et al. Water-soluble non-starch polysaccharides of root and tuber crops: extraction, characteristics, properties, bioactivities, and applications. Critical Reviews in Food Science and Nutrition, v. 62, n. 9, p. 2309-2341, 2022. DOI: https://doi.org/10.1080/10408398.2020.1852388
BATIHA, G. E. S. et al. Uncaria tomentosa (Willd. ex Schult.) DC.: A Review on Chemical Constituents and Biological Activities. Applied sciences, v. 10, n. 8, p. 2668, 2020. DOI: https://doi.org/10.3390/app10082668
CHAGAS, R. B. et al. Planejamento familiar em aspectos reprodutivos para casais com infertilidade. Revista Ibero-Americana de Humanidades, Ciências e Educação, v. 6, n. 11, p. 231-249, 2020. DOI: https://doi.org/10.51891/rease.v6i11.4895
FÉLIS, K. C.; ALMEIDA, R. J. Perspectiva de casais em relação à infertilidade e reprodução assistida: uma revisão sistemática. Reprodução & Climatério, v. 31, n. 2, p.105-111, 2016. DOI: https://doi.org/10.1016/j.recli.2016.01.004
FELIX, F. J. et al. Utilização de plantas medicinais na elaboração de garrafadas para fins terapêuticos no semiárido brasileiro. Research, Society and Development, v. 11, n. 16, e535111634508, 2022. DOI: https://doi.org/10.33448/rsd-v11i16.34508
GADELHA, C. S. et al. Estudo bibliográfico sobre o uso das plantas medicinais e fitoterápicos no Brasil. Revista Verde de Agroecologia e Desenvolvimento Sustentável, v. 8, n. 5, p. 208-212, 2013.
GLAZER, I. et al. Partial identification of antifungal compounds from Punica granatum pell extracts. Journal of Agricultural and Food Chemistry, v. 60, p. 4841-8, 2012. DOI: https://doi.org/10.1021/jf300330y
MINISTÉRIO DA SAÚDE. Resolução da Diretoria Colegiada – RDC No 26. Brasília: Agência Nacional de Vigilância Sanitária, 2014.
PANDEY, V. K. et al. Bioactive properties of clove (Syzygium aromaticum) essential oil nanoemulsion: A comprehensive review. Heliyon, v. 10, n. 1, p. e22437-e22437, 2024. DOI: https://doi.org/10.1016/j.heliyon.2023.e22437
PASSOS, M. M. B. et al. A disseminação cultural das garrafadas no Brasil: um paralelo entre medicina popular e legislação sanitária. Saúde em Debate, v. 42, n. 116, p. 248–262, 2018. DOI: https://doi.org/10.1590/0103-1104201811620
PEREIRA, P. R. et al. Tarin, a Potential Immunomodulator and COX‐Inhibitor Lectin Found in Taro (Colocasia esculenta). Comprehensive reviews in food science and food safety, v. 17, n. 4, p. 878-891, 2018. DOI: https://doi.org/10.1111/1541-4337.12358
SILVA, R. L.; TEIXEIRA R. Phenolic profile and biological potential of Endopleura uchi extracts. Asian Pacifica Journal of Tropical Medicine, v. 8, n. 11, p.889-897, 2015. DOI: https://doi.org/10.1016/j.apjtm.2015.10.013
SILVA, S. L. et al. Antimicrobial activity of bergenin from Endopleura uchi (Huber) Cuatrec. Acta Amazonica, v. 39, n. 1, p. 187-191, 2009. DOI: https://doi.org/10.1590/S0044-59672009000100019
Downloads
Published
How to Cite
License
Copyright (c) 2024 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
This work is licensed under a Creative Commons Attribution 4.0 International License.
Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.
