BIOACTIVE METABOLITES PRESENT IN A BOTTLE INDICATED FOR THE TREATMENT OF FEMALE INFERTILITY, PREPARED ACCORDING TO AN INTERNET RECIPE

Abstract

Among the preparations made with medicinal plants, the "garrafada" is one of the most popular. It can be bought in popular stores or prepared at home. Although the use of garrafadas is a common practice in Brazil, there is no reference to such products in legislation. This research evaluated the recipe for a bottle indicated to treat female infertility, composed of pomegranate (Punica granatum L.), cat's claw (Uncaria tomentosa), yellow uxi (Endopleura uchi), clove (Syzygium aromaticum) and yam (Colocasia esculenta (L.) Schott). Initially, a literature search was carried out to see if these species contained metabolites with proven pharmacological activities related to the treatment of infertility. Extracts of each of the plant species and of all the species together in methanol and wine were then prepared by maceration to check for the presence of the chemical markers and to compare the efficiency of the extractions. The chemical composition of the systems was determined by analyzing the spectra obtained by ESI-MS.The results showed that the plant species have metabolites with pharmacological action related to the treatment of infertility. The methanol extracts had a higher number of metabolites than the extracts prepared in wine, corroborating the theory that the extraction system used in garrafadas is not the most efficient. The phytopharmaceuticals found in the garrafada, which have pharmacological actions related to the treatment of infertility, were isocoumarin bergenin, gallic acid and apeginin.