CHART OF RECONSTITUTION AND DILUTION OF INJECTABLE MEDICATIONS IN PRIMARY HEALTH CARE OF THE HEALTH DEPARTMENT OF THE FEDERAL DISTRICT

Abstract

The preparation and reconstitution of injectable medications represent critical stages of pharmaceutical and nursing practice, especially within Primary Health Care, where the diversity of drugs requires clear protocols to ensure patient safety. The lack of standardization in these processes can result in dosage errors, chemical instability, and therapeutic failures, compromising the quality of care. This study aimed to propose a standardized chart for the reconstitution and dilution of injectable medications used in the Primary Health Care Network of the Federal District Health Department (SES-DF), supporting multidisciplinary teams in safe and effective preparation. It is a qualitative, exploratory, and documentary study based on literature review and field research in a basic health unit, using the Essential Medicines List (REME) as a reference. As a result, a chart was developed including 33 drugs from different therapeutic classes, such as antimicrobials, psychotropics, analgesics, anti-inflammatory agents, and gastroprotective agents, presenting information on diluents, volumes, stability, and storage conditions. The instrument serves as a quick-reference material, contributing to the standardization of practices and reduction of risks during the preparation of injectables. The standardization of reconstitution processes is an essential strategy to prevent failures, optimize workflow, and strengthen patient safety, emphasizing the pharmacist’s role as a mediator of the rational use of medicines.