PROTECTIVE VENTILATION PROTOCOL IN OBESE PATIENTS: STRATEGIES FOR PULMONARY FUNCTION OPTIMIZATION AND COMPLICATION REDUCTION

Abstract

Obesity imposes severe alterations on respiratory mechanics, making ventilatory management in intensive care a clinical challenge subject to great care variability. The objective of this study was to develop a protective mechanical ventilation protocol for critically ill obese patients. Method: This is an applied methodological study based on a narrative literature review (2020-2025). The evidence supported the creation of an institutional protocol for the Hospital Municipal Ronaldo Gazolla (RJ), aimed at standardizing multidisciplinary care. Results: The developed protocol establishes decisive maneuvers: mandatory pre-oxygenation with Non-Invasive Ventilation (NIV); positioning in Beach Chair or reverse Trendelenburg for intra-abdominal pressure relief; mandatory tidal volume calculation (6-8 mL/kg) by predicted body weight using knee or ulna height; rigorous driving pressure monitoring; individualized PEEP titration; prone positioning as rescue; and immediate prophylactic institution of NIV post-extubation. Conclusion: The instrument translates pathophysiological complexity into a practical bedside algorithm. In a scenario of intensive routine and different levels of staff expertise, the protocol acts as a barrier against empirical errors, reducing care variability, mitigating the risk of Ventilator-Induced Lung Injury (VILI), and paving the way for improved clinical outcomes.

Author Biographies

Marcelle Maria Vieira Saldanha, Hospital Municipal Ronaldo Gazolla

Fisioterapeuta Residente em Atenção em Terapia Intensiva.

Diane Manhães de Figueiredo, Hospital Municipal Ronaldo Gazolla

Fisioterapeuta Residente em Atenção em Terapia Intensiva.

Gabriel Rodrigues Cesário, Hospital Municipal Ronaldo Gazolla

Fisioterapeuta Residente da atenção em Terapia Intensiva.

Iuri Moreira Berrondo, Hospital Municipal Ronaldo Gazolla

Fisioterapeuta Residente da atenção em Terapia Intensiva.

Narjara Lopes Alves Nascimento, Hospital Municipal Ronaldo Gazolla

Fisioterapeuta Residente em Atenção em Terapia Intensiva.

Rafaelly Cristina Martins Leão, Universidade Veiga de Almeida

Graduanda de Fisioterapia.

Allyevison Ulisses Alves Cavalcanti, Hospital Municipal Ronaldo Gazolla

Fisioterapeuta. Mestre em Modelos de Decisão e Saúde. Doutor em Empidemiologia em Saúde Pública Ensp/FIOCRUZ.

 

References

ALEXANDRE, A. R. et al. Impact of Height Estimation on Tidal Volume Calculation for Protective Ventilation-A Prospective Observational Study. Critical Care Explorations, v. 3, n. 5, p. e0422, 2021.

AMIB; SBPT. Associação de Medicina Intensiva Brasileira & Sociedade Brasileira de Pneumologia e Tisiologia. Orientações Práticas em Ventilação Mecânica. São Paulo: AMIB; SBPT, 2024.

ANDERSON, M. R.; SHASHATY, M. G. S. Impact of Obesity in Critical Illness. CHEST, v. 160, n. 6, p. 2135-2145, 2021.

AYALON, I.; BODILLY, L.; KAPLAN, J. The Impact of Obesity on Critical Illnesses. Shock, v. 56, n. 5, p. 691-700, 2021.

BARBAS, C. S. V. et al. Brazilian recommendations of mechanical ventilation 2013. Part 2. Revista Brasileira de Terapia Intensiva, v. 26, n. 3, p. 215-239, 2014.

BORDONI, B.; ESCHER, A. R. Obesity and the Importance of Breathing. Cureus, v. 17, n. 1, p. e77431, 2025.

BRODSKY, J. B. et al. Morbid obesity and tracheal intubation. Anesthesia and Analgesia, v. 94, p. 732-736, 2002.

CAVALCANTI, A. B. et al. Effect of Lung Recruitment and Titrated Positive End-Expiratory Pressure (PEEP) vs Low PEEP on Mortality in Patients With Acute Respiratory Distress Syndrome: A Randomized Clinical Trial. JAMA, v. 318, n. 14, p. 1335-1345, 2017.

CHEN, X. et al. Effects of prone positioning on oxygenation and survival in obese patients with severe acute respiratory distress syndrome: A retrospective cohort study. Frontiers in Medicine, v. 11, p. 12778116, 2024.

CHUMLEA, W. C.; ROCHE, A. F.; STEINBAUGH, M. L. Estimating stature from knee height for persons 60 to 90 years of age. Journal of the American Geriatrics Society, v. 33, n. 2, p. 116-120, 1985.

DE JONG, A. et al. How to ventilate obese patients in the ICU. Intensive Care Medicine, v. 46, n. 12, p. 2423-2435, 2020.

DE JONG, A. et al. Non-invasive ventilation after extubation in obese patients: the EXTUBOBESE trial. Intensive Care Medicine, v. 51, n. 1, p. 1-12, 2025.

DE JONG, A.; CHANQUES, G.; JABER, S. Mechanical ventilation in obese ICU patients: from intubation to extubation. Critical Care, v. 21, n. 1, p. 63, 2017.

DE SANTIS SANTIAGO, R. R. et al. Driving pressure in obese patients with acute respiratory distress syndrome: one size fits all? Journal of Thoracic Disease, v. 13, n. 4, p. 2635-2638, 2021.

DIXON, A. E.; PETERS, U. The effect of obesity on lung function. Expert Review of Respiratory Medicine, v. 12, n. 9, p. 755-767, 2018.

ELIA, M. The malnutrition universal screening tool (MUST). Redditch: BAPEN, 2003.

EL-SOLH, A. A. et al. Noninvasive ventilation for prevention of post-extubation respiratory failure in obese patients. European Respiratory Journal, v. 28, p. 588-595, 2006.

FERREIRA, J. C. et al. Joint statement on evidence-based practices in mechanical ventilation: suggestions from two Brazilian medical societies. Jornal Brasileiro de Pneumologia, v. 51, n. 1, p. e20240255, 2025.

GRASSELLI, G. et al. ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies. Intensive Care Medicine, v. 49, n. 7, p. 727-759, 2023.

JONES, R. L.; NZEKWU, M. M. The Effects of Body Mass Index on Lung Volumes. CHEST, v. 130, n. 3, p. 827-833, 2006.

KACMAREK, R. M. et al. Weaning patients with obesity from ventilatory support. Current Opinion in Critical Care, v. 27, n. 3, p. 311-319, 2021.

LUNDSTRØM, L. H. et al. High Body Mass Index Is a Weak Predictor for Difficult and Failed Tracheal Intubation: A Cohort Study. Anesthesiology, v. 110, n. 2, p. 266-274, 2009.

MAHUL, M. et al. Spontaneous breathing trial and post-extubation work of breathing in morbidly obese critically ill patients. Critical Care, v. 20, p. 346, 2016.

MARTÍNEZ-CAMACHO, M. Á. et al. Physical and respiratory therapy in the critically ill patient with obesity: a narrative review. Frontiers in Medicine, v. 11, p. 1321692, 2024.

MELO, A. P. F. et al. Métodos de estimativa de peso corporal e altura em adultos hospitalizados: uma análise comparativa. Revista Brasileira de Cineantropometria e Desempenho Humano, v. 16, n. 4, p. 475, 2014.

MONTEIRO, R. S. C. et al. Estimativa de peso, altura e índice de massa corporal em adultos e idosos americanos: revisão. Comunicação em Ciências da Saúde, v. 20, n. 4, p. 341-350, 2009.

MOON, T. S. et al. The influence of morbid obesity on difficult intubation and difficult mask ventilation. Journal of Anesthesia, v. 33, n. 1, p. 96-102, 2019.

O'BRIEN JUNIOR, J. M. et al. Excess body weight is not independently associated with outcome in mechanically ventilated patients with acute lung injury. Annals of Internal Medicine, v. 140, p. 338-345, 2004.

PERILLI, V. et al. The effects of the reverse trendelenburg position on respiratory mechanics and blood gases in morbidly obese patients during bariatric surgery. Anesthesia and Analgesia, v. 91, p. 1520-1525, 2000.

RABEC, C. et al. Ventilation in the obese: physiological insights and management. European Respiratory Review, v. 34, n. 176, p. 240190, 2025.

ROMERO, C. S.; CORTEGIANI, A.; LÜDI, M. M. New insights in mechanical ventilation in the obese patients. Journal of Clinical Anesthesia, v. 92, p. 111268, 2024.

ROUZÉ, A. et al. Prone position in obese patients with acute respiratory distress syndrome after cardio-thoracic surgery. European Journal of Cardio-Thoracic Surgery, v. 66, n. 6, ezae398, nov. 2024.

SCHETZ, M. et al. Obesity in the critically ill: a narrative review. Intensive Care Medicine, v. 45, n. 6, p. 757-769, 2019.

SEVRANSKY, J. E. et al. Protocols and Hospital Mortality in Critically III Patients: The United States Critical Illness and Injury Trials Group Critical Illness Outcomes Study. Critical Care Medicine, v. 43, n. 10, p. 2076-2084, 2015.

SPRUNG, J. et al. The effects of tidal volume and respiratory rate on oxygenation and respiratory mechanics during laparoscopy in morbidly obese patients. Anesthesia and Analgesia, v. 97, p. 268-274, 2003.

SWINBURN, B. A. et al. The global obesity pandemic: shaped by global drivers and local environments. The Lancet, v. 378, n. 9793, p. 804-814, 2011.

THE ACUTE RESPIRATORY DISTRESS SYNDROME NETWORK. Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The New England Journal of Medicine, v. 342, n. 18, p. 1301-1308, 2000.

VALENZA, F. et al. Effects of the beach chair position, positive end-expiratory pressure, and pneumoperitoneum on respiratory function in morbidly obese patients during anesthesia and paralysis. Anesthesiology, v. 107, p. 725-732, 2007.

WHO - WORLD HEALTH ORGANIZATION. Obesity: preventing and managing the global epidemic. Report of a WHO consultation. World Health Organ Tech Rep Ser, v. 894, 2000.

WORLD OBESITY FEDERATION. World Obesity Atlas 2025. London: World Obesity Federation, 2025.

XAVIER, T. B. et al. Individualized positive end-expiratory pressure reduces driving pressure in obese patients during laparoscopic surgery. Frontiers in Physiology, v. 15, p. 1383167, 2024.

How to Cite

Vieira Saldanha, M. M., Manhães de Figueiredo, D., Rodrigues Cesário, G., Moreira Berrondo, I., Lopes Alves Nascimento, N., Cristina Martins Leão, R., & Alves Cavalcanti, A. U. (2026). PROTECTIVE VENTILATION PROTOCOL IN OBESE PATIENTS: STRATEGIES FOR PULMONARY FUNCTION OPTIMIZATION AND COMPLICATION REDUCTION. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 7(3), e737363. https://doi.org/10.47820/recima21.v7i3.7363