ESTIMATING ARTERIAL AND VENOUS DYNAMICS THROUGH A VENOUS OCCLUSION PLETHYSMOGRAPHY-BASED WINDKESSEL MODEL: PRELIMINARY RESULTS
Abstract
This study presents preliminary findings from a pilot investigation involving five healthy subjects to evaluate a vascular mechanics model applied to venous occlusion plethysmography. The proposed model characterizes arterial and venous mechanical properties at baseline and enables dynamic parameter estimation during post-occlusion recovery. Reactive hyperemia induced by forearm venous occlusion was assessed under baseline conditions and after physiological interventions (ibuprofen administration and exercise). The model quantified transient hemodynamic responses, consistently showing decreases in arterial and venous resistances and increases in venous compliance, followed by gradual recovery toward baseline values. Condition-dependent differences were identified: resistance reductions were more pronounced after ibuprofen administration, whereas venous compliance exhibited greater enhancement following exercise. These results demonstrate the model’s sensitivity to pharmacological and physiological modulation of vascular function. The proposed framework offers a noninvasive approach for the simultaneous assessment of arterial and venous dynamics and may contribute to opening new paths for cardiovascular function assessment.
Author Biographies
Federal Institute of Education, Science and Technology of Rio de Janeiro. Graduated in Physiotherapy and Social Sciences. Specialist in Biomechanics. Master and Doctor in Biomedical Engineering (COPPE/UFRJ).
Professor at the Laboratory of Exercise Sciences (LACE/UFF) of the Physiology Department at Fluminense Federal University. Graduated in Medicine. Master in Biological Sciences (Biophysics/UFRJ). Doctor in Sciences. Specialist in Exercise and Sports Medicine and in Cardiology
Automation engineer at TRANSPETRO (Petrobras Transporte S/A). Master in Biomedical Engineering (COPPE/UFRJ).
Professor in the Biomedical Engineering Program (COPPE) and in the Graduate Program in Surgical Sciences of the Department of Surgery at the Faculty of Medicine of the Federal University of Rio de Janeiro (UFRJ). Electronic Engineer. Master in Biomedical Engineering and Doctor in Electrical Engineering.
Professor of the Biomedical Engineering Program (COPPE/UFRJ) and of the Department of Electronics and Computing of the Polytechnic School (UFRJ). Master and Doctor in Electrical Engineering (UFRJ). Coordinator of the Biomedical Instrumentation Laboratory (PEB/COPPE/UFRJ).
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