FACTORS ASSOCIATED WITH SEPSIS MORTALITY IN PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT

Abstract

Sepsis is a leading cause of mortality in intensive care units (ICUs), accounting for a high number of deaths and a significant burden on healthcare systems. Early identification of factors associated with the risk of death is fundamental to optimizing clinical management and improving outcomes for critically ill patients. The objective of this study is to analyze the factors associated with mortality in patients with sepsis admitted to an intensive care unit. This is a retrospective observational study conducted with patients diagnosed with sepsis and admitted to the ICU. Sociodemographic, clinical, and laboratory variables were evaluated, including age, comorbidities, infectious focus, hemodynamic parameters, and laboratory markers. The results showed higher mortality in patients with advanced age, presence of comorbidities, hemodynamic instability, and multiple organ dysfunction. Laboratory abnormalities, such as elevated lactate and renal dysfunction, were also associated with worse outcomes. Mortality from sepsis in the ICU is related to multiple clinical and laboratory factors, highlighting the importance of early identification of high-risk patients. Recognizing these factors can contribute to more targeted interventions and potentially reduce mortality in critically ill patients.

Author Biographies

Leticia Diman Pereira, Faculdade de Medicina de Mogi das Cruzes

Graduate in Medicine.

Namibia Pimenta Guevara , Universidade Federal do Rio de Janeiro

Graduate in Medicine.

Darliane Lima Muniz, Instituto de Educação Médica - Estácio de Sá - Campus Iguatu

Graduate in Medicine.

Ruthiany Costa da   Silva, Universidade Estadual do Rio de Janeiro - Faculdade de Ciências Médicas

Medical student.

Bruno Matheus Dantas de Almeida, UNICEUB-Brasília

Medical student.

Eduardo da Cunha Oliveira, Faculdade Metropolitana de Manaus

Nursing student.

Mayara Freitas Soares, AGES-Jacobina.  Jacobina, Bahia

Medical student, AGES-Jacobina College. Jacobina, Bahia, Brazil.

Fernanda Fernandes Ferreira , AGES-Jacobina.  Jacobina, Bahia

Medical student, AGES-Jacobina College. Jacobina, Bahia, Brazil.

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How to Cite

Pereira, L. D. ., Guevara , N. P., Muniz, D. L., Silva,R.C.da , Almeida, B. M. D. de, Oliveira, E. da C. ., Soares, M. F. ., & Ferreira , F. F. . (2026). FACTORS ASSOCIATED WITH SEPSIS MORTALITY IN PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 7(4), e747735. https://doi.org/10.47820/recima21.v7i4.7735