TECHNOLOGICAL OVERVIEW OF RED PROPOLIS FROM ALAGOAS: PATENT ANALYSIS AND IDENTIFIED BIOACTIVE COMPOUNDS
Abstract
Red Propolis from Alagoas (PVA) stands out for its unique biological properties and Geographical Indication, recognized by the Denomination of Origin (DO) seal, representing a resource with high innovation potential. This study aimed to conduct a technological prospecting based on patent documents related to PVA to map innovation areas and identify the key stakeholders involved. The methodology, of an exploratory and quantitative nature, consisted of searches in the USPTO, Espacenet, Patentscope, and INPI databases, without the establishment of a time frame. The results identified 31 patent documents, with a peak in filings in 2020, driven by public funding calls. Findings indicate non-linear growth in technological development, concentrated in the health sector, particularly in classes A61K and A61P. Innovations focused on advanced drug delivery systems, such as microencapsulated and nanostructured systems, as well as semi-solid formulations for dermatological and dental applications, predominate. The prospecting identified the protection of specific phytochemicals, such as Bolusanthol D and Oblongifolin A, in bioactive compositions, with the Federal University of Alagoas (UFAL) consolidating itself as the leading applicant (51.6%). It is concluded that, while the technological development of PVA is in a consolidation phase driven by academic institutions, a significant gap in technology transfer to the productive sector persists, revealing a technological gap that limits PVA's access to the market and public health.
Author Biographies
Graduated in Pharmacy with a specialization in Clinical Analysis from the Federal University of Ceará (UFC). Holds postgraduate specializations in Public Management (UNEAL), Pharmaceutical Care Management (ESP/CE), and Institutional Support with an emphasis on Primary Health Care (UNICAMP). Master’s degree in Pharmaceutical Sciences from the Federal University of Alagoas (UFAL). Ph.D. candidate in the Graduate Program in Drug Development and Technological Innovation (PPgDITM) at the Federal University of Ceará (UFC). Civil servant at the State Health Secretariat of Alagoas.
Ph.D. candidate in Drug Development and Technological Innovation (PPGDITM) at the Federal University of Ceará (UFC). Holds a Master’s degree in Pharmaceutical Sciences from the Federal University of Ceará (UFC) and a Bachelor’s degree in Pharmacy from UFC. Specialist in Phytotherapy from Faculdade Faveni and has advanced training in Public Health from the Metropolitan Faculty of the State of São Paulo (FAMEESP).
Undergraduate Pharmacy student at the Federal University of Ceará (UFC). Scholarship recipient of the Institutional Program for Technological Development and Innovation Initiation Scholarships (PIBITI/UFC).
Undergraduate Pharmacy student at the Federal University of Ceará (UFC). Student researcher in the Institutional Scientific Initiation Scholarship Program (PIBIC/UFC).
Holds a Bachelor’s degree in Pharmacy from the Federal University of Ceará (UFC), a specialization in Medicinal Chemistry from the Federal University of Minas Gerais (UFMG), and Master’s and Ph.D. degrees in Chemistry from the Federal University of Ceará. Currently serves as Full Professor in the Pharmacy Program at the Federal University of Ceará, teaching the courses Pharmacognosy and Phytotherapy.
Bachelor’s degree in Pharmacy from the Federal University of Alagoas – Institute of Pharmaceutical Sciences (ICF/UFAL). Holds a Master’s degree in Pharmaceutical Sciences from the Graduate Program in Pharmaceutical Sciences (PPGCF/ICF/UFAL) and is currently a Ph.D. candidate in the same program at the Institute of Pharmaceutical Sciences of the Federal University of Alagoas (PPGCF/ICF/UFAL).
Bachelor’s degree in Pharmacy from the Federal University of Alagoas – Institute of Pharmaceutical Sciences (ICF/UFAL). Holds a Master’s degree in Pharmaceutical Sciences from the Graduate Program in Pharmaceutical Sciences (PPGCF/ICF/UFAL) and is currently a Ph.D. candidate in the same program at the Institute of Pharmaceutical Sciences of the Federal University of Alagoas (PPGCF/ICF/UFAL).
Holds a Bachelor’s degree and a Ph.D. in Pharmacy from the Federal University of Paraíba, with a specialization in Bioactive Natural and Synthetic Products. Recipient of a CNPq Productivity in Technological Development and Innovative Extension Scholarship (Level 2 – CA). Currently serves as Full Professor at the Institute of Pharmaceutical Sciences of the Federal University of Alagoas, where he teaches the courses Pharmaceutical Technology and Pharmaceutics.
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