BIFOSFONATOS: EVALUACIÓN DE LOS CONOCIMIENTOS DE ODONTOLOGÍA
Resumen
Los bifosfonatos (BF) son fármacos muy utilizados en medicina, especialmente en el tratamiento del cáncer y la osteoporosis y otras enfermedades óseas. Actúan inhibiendo la actividad osteoclástica, alterando así toda la remodelación ósea; se acumulan en el hueso y pueden causar necrosis. Las osteonecrosis de los maxilares relacionadas con los bifosfonatos suelen ir precedidas de un tratamiento odontológico, por lo que es un papel fundamental del cirujano dentista (DC) diagnosticar y tratar estas patologías, y sobre todo prevenirlas. De esta manera, se debe evitar la negligencia dentro de una anamnesis en relación con este fármaco, reduciendo así los riesgos de grandes mutilaciones y la pérdida de calidad de vida del paciente. Este estudio pretende evaluar el nivel de conocimiento de los dentistas sobre los bifosfonatos.
Biografía del autor/a
Acadêmico em odontologia pela Universidade Paulista - UNIP
Acadêmico em odontologia pela Universidade Paulista – UNIP
Acadêmico em odontologia pela Universidade Paulista – UNIP
Acadêmico em odontologia pela Universidade Paulista – UNIP
Acadêmico em odontologia pela Universidade Paulista – UNIP
Acadêmico em odontologia pela Universidade Paulista – UNIP
Faculdade de Odontologia do Centro Universitário - ICESP
Clínica privada, Goiânia, Goiás
Clínica privada, Goiânia, Goiás
Faculdade de Odontologia do Centro Universitário ICESP
Referencias
MARX, R. E. et al. Bisphosphonate-induced exposed bone (osteonecrosis/osteopetrosis)
of the jaws: Risk factors, recognition, prevention, and treatment. Journal of Oral and Maxillofacial Surgery, v. 63, n. 11, p. 1567–1575, 2005.
MAVROKOKKI, T. et al. Nature and Frequency of Bisphosphonate-Associated Osteonecrosis of the Jaws in Australia. Journal of Oral and Maxillofacial Surgery, v. 65, n. 3, p. 415–423, 2007.
EDWARDS, B. J. et al. Updated recommendations for managing the care of patients receiving oral bisphosphonate therapy: an advisory statement from the American Dental Association Council on Scientific Affairs. Journal of the American Dental Association (1939), v. 139, n. 12, p. 1674–1677, 2008.
LO, J. C. et al. Prevalence of Osteonecrosis of the Jaw in Patients With Oral Bisphosphonate Exposure. Journal of Oral and Maxillofacial Surgery, v. 68, n. 2, p. 243–253, 2010.
BARASCH, A. et al. Risk factors for osteonecrosis of the jaws: a case-control study from the CONDOR dental PBRN. Journal of dental research, v. 90, n. 4, p. 439–44, 2011.
DINIZ-FREITAS, M. et al. Oral bisphosphonate-related osteonecrosis of the jaws: Clinical characteristics of a series of 20 cases in Spain. Medicina Oral, Patologia Oral y Cirugia Bucal, v. 17, n. 5, 2012.
GÓMEZ-MORENO, G. et al. Bisphosphonate-associated osteonecrosis of the jaw 2 years after teeth extractions: A case report solved with non-invasive treatment. European Review for Medical and Pharmacological Sciences, v. 18, n. 9, p. 1391–1397, 2014.
TARDAST, A. et al. Bisphosphonate associated osteomyelitis of the jaw in patients with bony exposure: prevention, a new way of thinking. Journal of applied oral science : revista FOB, v. 23, n. 3, p. 310–4, 2015.
ROGERS, S. N. et al. United Kingdom nationwide study of avascular necrosis of the jaws including bisphosphonate-related necrosis. British Journal of Oral and Maxillofacial Surgery, v. 53, n. 2, p. 176–182, 2015.
DE LIMA, P. B. et al. Knowledge and attitudes of Brazilian dental students and dentists regarding bisphosphonate-related osteonecrosis of the jaw. Supportive Care in Cancer, v. 23, n. 12, p. 3421–3426, 2015.
NISI, M. et al. Risk factors influencing BRONJ staging in patients receiving intravenous bisphosphonates: A multivariate analysis. International Journal of Oral and Maxillofacial Surgery, v. 44, n. 5, p. 586–591, 2015.
