ASCARIASIS: EPIDEMIOLOGY, CLINICAL ASPECTS, AND PERSPECTIVES ON THE USE OF ARTIFICIAL INTELLIGENCE
DOI:
https://doi.org/10.47820/recima21.v6i11.6756Keywords:
ascariasis, epidemiology, Parasitic diseases, public health surveillanceAbstract
Ascariasis, caused by the intestinal nematode Ascaris lumbricoides, represents one of the most prevalent helminthic infections worldwide. Given its high prevalence and significant impact on public health, a comprehensive understanding of its epidemiological characteristics, clinical manifestations, and management strategies is imperative. Recent technological advancements, particularly the application of artificial intelligence, are being explored to enhance diagnostic accuracy and therapeutic approaches. This study aims to conduct a narrative review of ascariasis, focusing on its epidemiology, clinical manifestations, and therapeutic strategies. The review was conducted through systematic searches of major biomedical databases, including PubMed, Scopus, Google Scholar, and SciELO. Relevant articles published in recent years were selected based on criteria such as scientific impact, clinical relevance, and incorporation of technological advancements. The data underscore that ascariasis remains a significant public health concern, particularly in regions with inadequate sanitation. Clinical manifestations range from asymptomatic cases to severe conditions, including intestinal obstruction and pulmonary complications. Therapeutically, antihelminthic drugs remain the cornerstone of treatment; however, challenges such as drug resistance and reinfection necessitate complementary approaches, including prophylactic measures. Recent studies highlight the pivotal role of artificial intelligence in improving diagnostic precision and personalizing therapeutic interventions. A thorough understanding of its epidemiological, clinical, and therapeutic aspects is essential for effective management. The integration of artificial intelligence into the diagnosis and treatment of ascariasis holds promising potential, offering opportunities for more effective and personalized approaches.
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References
AHMED, Molla Imaduddin; SPOONER, Brendan; ISHERWOOD, John; LANE, Mark; ORROCK, Emma; DENNISON, Ashley. A Systematic Review of the Barriers to the Implementation of Artificial Intelligence in Healthcare. Cureus, [S. L.], p. 0, 4 out. 2023. Springer Science and Business Media LLC. http://dx.doi.org/10.7759/cureus.46454.
ASM, Al Amin; WADHWA Roopma. “Helminthiasis.” StatPearls Publishing, 2020. www.ncbi.nlm.nih.gov/books/NBK560525/.
BEKELE, Temesgen; LACHISA, Lata; TSEGAYE, Arega; BACHA, Ketema; KETEMA, Tsige. Efficacy of Albendazole and Mebendazole Against Soil Transmitted Infections among Pre-School and School Age Children: a systematic review and meta-analysis. Journal of Epidemiology and Global Health, [S. L.], v. 14, n. 3, p. 884-904, 2 maio 2024. Springer Science and Business Media LLC. http://dx.doi.org/10.1007/s44197-024-00231-7.
CDC - CENTERS FOR DISEASE CONTROL AND PREVENTION. Parasites: ascariasis. [S. l.]: CDC, 2019. Disponível em: https://www.cdc.gov/dpdx/ascariasis/index.html. Acesso em: mar. 2025.
CHIELLE, Eduardo Ottobelli; KUIAVA, Eliseu Luiz; FAUST, Guilherme Augusto; CHIELLE, Ana Paula Ottobelli; KUIAVA, Victor Antônio; ALVES, Roberson Junior Fernandes. Desenvolvimento de sistema estruturado com inteligência artificial para apoio no diagnóstico de parasitoses intestinais. Clinical & Biomedical Research, [S. L.], p. 0, 29 mar. 2021. Tikinet Edicao Ltda. - EPP. http://dx.doi.org/10.22491/2357-9730.105362.
CONTERNO, Lucieni O; TURCHI, Marilia D; CORRÊA, Ione; ALMEIDA, Ricardo A. Anthelmintic drugs for treating ascariasis. Cochrane Database ff Systematic Reviews, [S. L.], v. 2020, n. 4, p. 0, 14 abr. 2020. http://dx.doi.org/10.1002/14651858.cd010599.pub2.
COSTA, Cleonice Duarte da Silva; OLIVEIRA, Kely Alves de; DIAS, Leonardo Morais; SANTOS, Patrícia Rosa dos; NASCIMENTO, Raquel Cristina Freitas. ANTIPARASITÁRIO E A VITAMINA A: sua atuação no combate ao parasitismo por ascaridíase. Revista Ibero-Americana de Humanidades, Ciências e Educação, [S. L.], v. 7, n. 5, p. 808-828, 14 jun. 2021. http://dx.doi.org/10.51891/rease.v7i5.1272.
CURE-BOLT, Nancy; PEREZ, Fernando; BROADFIELD, Lindsay A.; LEVECKE, Bruno; HU, Peter; OLEYNICK, John; BELTRÁN, María; WARD, Peter; STUYVER, Lieven. Artificial intelligence-based digital pathology for the detection and quantification of soil-transmitted helminths eggs. Plos Neglected Tropical Diseases, [S. L.], v. 18, n. 9, p. 0, 30 set. 2024. http://dx.doi.org/10.1371/journal.pntd.0012492.
DE LIMA CORVINO, D. F.; HORRALL, S. Ascariasis. [Atualizado em 17 jul. 2023]. In: STATPEARLS [Internet]. Treasure Island (FL): StatPearls Publishing, 2025 jan. Disponível em: https://www.ncbi.nlm.nih.gov/books/NBK430796/. Acesso em: mar. 2025.
HARRISON, Tinsley Randolph. Harrison's principles of internal medicine. 21st ed. New York: McGraw-Hill, c2022. 2 v. ISBN 978-1-264-26846-7.
HINRICHSEN, S. L. DIP: Doenças Infecciosas e Parasitárias. 2. ed. Rio de Janeiro: Guanabara Koogan, 2009. ISBN 978-85-277-3120-5.
HOLLAND, Celia; SEPIDARKISH, Mahdi; DESLYPER, Gwendoline; ABDOLLAHI, Ali; VALIZADEH, Soghra; MOLLALO, Abolfazl; MAHJOUR, Sanaz; GHODSIAN, Sahar; ARDEKANI, Ali; BEHNIAFAR, Hamed. Global prevalence of Ascaris infection in humans (2010–2021): a systematic review and meta-analysis. Infectious Diseases of Poverty, [S. L.], v. 11, n. 1, p. 0, 18 nov. 2022. http://dx.doi.org/10.1186/s40249-022-01038-z.
JAMESON J. L.; FAUCI A. S.; KASPER D. L.; HAUSER S. L.; LONGO D. L.; LOSCALZO J. (eds). Harrison’s Principles of Internal Medicine. 21st ed. New York, NY: McGraw-Hill; 2022.
LEÓN, P. P.; RACCA, L.; MENÉNDEZ, M. et al. Acción de Ascaris lumbricoides sobre la carga aniónica de eritrocitos y eritrocitos desializados. Acta Bioquímica Clínica Latinoamericana, Buenos Aires, v. 56, n. 2, p. 247-256, 2024.
LEUNG, Alexander K. C.; LEUNG, Amy A. M.; WONG, Alex H. C.; HON, Kam L. Human Ascariasis: an updated review. Recent Patents on Inflammation & Allergy Drug Discovery, [S. L.], v. 14, n. 2, p. 133-145, 15 jan. 2021. http://dx.doi.org/10.2174/1872213x14666200705235757.
MAGUIRE, J. H. Intestinal nematodes (roundworms). In: BENNETT, J. E.; DOLIN, R.; BLASER, M. J. (Ed.). Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 9. ed. Philadelphia: Elsevier, 2020. ISBN 978-0-323-55027-7.
MALIK, Hurais; DIN, Muhammad Fazal Ud; FAIZAN, Muhammad Aqib; REHMAN, Tooba; HUDAIB, Muhammad; SHAH, Syed Muhammad Abdullah; KHAN, Abdullah Abid; AMIR, Syeda Fatima; FRAZ, Musarrat; KHALID, Maham. Efficacy and safety of ivermectin–albendazole combination versus ivermectin or albendazole monotherapy in soil-transmitted helminthiasis: a systematic review and meta-analysis. Medicine, [S. L.], v. 104, n. 3, p. 0, 17 jan. 2025. http://dx.doi.org/10.1097/md.0000000000041280.
MURRAY, Patrick R.; ROSENTHAL, Ken S.; PFALLER, Michael A. Microbiologia Médica. 9. ed. Rio de Janeiro: GEN Guanabara Koogan, 2023.
NEREU, Jonatha França. Revisão bibliográfica: Ascaris lumbricoides e a Ascaridíase. 2023. 65 f. TCC (Graduação) - Curso de Graduação Farmácia-Bioquímica, Universidade Estadual Paulista, Araraquara, 2023. Disponível em: https://repositorio.unesp.br/server/api/core/bitstreams/412354bc-66fa-4a4d-9cab-1db74e5e10dd/content. Acesso em: 24 mar. 2025.
NETO, V. A. Parasitologia: Uma Abordagem Clínica. 4. ed. Rio de Janeiro: Elsevier, 2008. 480 p. ISBN 978-85-352-9987-3.
NEVES, David Pereira et al. Parasitologia Humana. 14. ed. Rio de Janeiro: Atheneu, 2022. 616 p. ISBN 978-85-388-0715-5.
NEVES, David Pereira. Parasitologia Dinâmica. 3. ed. São Paulo: Atheneu, 2009. 608 p. ISBN 978-85-388-0072-9.
SANTOMAURO, Rafael Alves; PINTO-FERREIRA, Fernanda; PIMONT, Nathália Miasato; MARQUES, Mariana da Silva; LEMOS, Maria Clara Soares; LADEIA, Winni Alves; BALBINO, Letícia Santos; NAVARRO, Italmar Teodorico. Parasitic contamination in vegetables for human consumption: a systematic review and meta-analysis. Revista Brasileira de Parasitologia Veterinária, [S. L.], v. 33, n. 3, p. 0, 2024. http://dx.doi.org/10.1590/s1984-29612024040.
SBP - SOCIEDADE BRASILEIRA DE PEDIATRIA. Parasitoses Intestinais: Diagnóstico E Tratamento. Rio de Janeiro: SBP, 2020.
SCHINDLER-PIONTEK, Markus; CHAUBAL, Nitin; DEHMANI, Sirine; CUI, Xin Wu; DONG, Yi; SHARMA, Malay; DIETRICH, Christoph F. Ascariasis, a review. Medical Ultrasonography, [S. L.], p. 0, 3 ago. 2021. http://dx.doi.org/10.11152/mu-3343.
SHALABY, Nehad; SHALABY, Naglaa. Effect of Ascaris lumbricoides infection on T helper cell type 2 in rural Egyptian children. Therapeutics and Clinical Risk Management, [S. L.], p. 379, mar. 2016. http://dx.doi.org/10.2147/tcrm.s94019.
SIQUEIRA-BATISTA, R.; GOMES, A. P.; SILVA SANTOS, S.; SANTANA, L. A. Parasitologia: fundamentos e prática clínica. Rio de Janeiro: Guanabara Koogan, 2020.
TEE, Mian Zi; LEE, Soo Ching; ER, Yi Xian; YAP, Nan Jiun; NGUI, Romano; EASTON, Alice V.; SIOW, Vinnie Wei Yin; NG, Kee Seong; BOEY, Christopher Chiong Meng; CHUA, Kek Heng. Efficacy of triple dose albendazole treatment for soil-transmitted helminth infections. Plos One, [S. L.], v. 17, n. 8, p. 0, 12 ago. 2022. http://dx.doi.org/10.1371/journal.pone.0272821.
WHO - WORLD HEALTH ORGANIZATION. “Soil-Transmitted Helminth Infections.” [S. l.]: WHO, 18 Jan. 2023. www.who.int/news-room/fact-sheets/detail/soil-transmitted-helminth-infections/.
ZAFAR, Aziz; ATTIA, Ziad; TESFAYE, Mehret; WALELIGN, Sosina; WORDOFA, Moges; ABERA, Dessie; DESTA, Kassu; TSEGAYE, Aster; AY, Ahmet; TAYE, Bineyam. Machine learning-based risk factor analysis and prevalence prediction of intestinal parasitic infections using epidemiological survey data. Plos Neglected Tropical Diseases, [S. L.], v. 16, n. 6, p. 0, 14 jun. 2022. http://dx.doi.org/10.1371/journal.pntd.0010517.
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