POSSÍVEIS BIOMARCADORES IMUNOLÓGICOS RELACIONADOS AO DIAGNÓSTICO DA DOENÇA PERIODONTAL
Resumo
A periodontite é uma doença inflamatória crônica que acomete os tecidos de suporte, incluindo o ligamento periodontal e o osso alveolar e afeta cerca de 11% da população mundial. Atualmente os parâmetros clínicos de profundidade de sondagem, sangramento à sondagem, nível clínico de inserção, índice de placa e exame radiográfico para análise de perda óssea tem sido utilizados como diagnóstico. Embora sejam simples e não invasivos, estes métodos clínicos não conseguem identificar pacientes altamente suscetíveis à progressão da doença periodontal. Identificar biomarcadores da doença é uma opção rápida e eficaz de rastreamento populacional para o planejamento de ações políticas públicas e medidas profiláticas. Foram analisados estudos de revisão sistemática, meta-análise, ensaios clínicos controlados aleatorizados (RCTs) e estudos publicados em revistas científicas, com a finalidade de avaliar a existência de novos biomarcadores para diagnóstico da doença periodontal.
Biografia do Autor
Graduação em Odontologia, Mestrado e Doutorado em Clínica Odontológica - área de concentração em Dentística pela FOP UNICAMP, Proficiência em Laser pela Academy of Laser Dentistry ALD-USA. Professor Pesquisador do PPG e Graduação em Odontologia da Universidade Guarulhos - UNG. Professor do curso de Odontologia da Universidade São Judas Tadeu - USJT. Faculty Associate do departamento Dentistry/Restorative Dental Sciences, do health Science Center da University of Florida.
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