USE OF BETABLOCKERS IN THE TREATMENT OF INFANTILE HEMANGIOMA

Authors

DOI:

https://doi.org/10.47820/recima21.v4i8.3731

Keywords:

Infantile hemangioma, propranolol, pediatrics, beta-blockers

Abstract

Introduction: Infantile hemangiomas (IHs) are common benign vascular tumors in children. Historical and current treatment options include medical therapy, surgical resection, laser therapy or direct intralesional steroid injections.  Objective: To group the main beta-blockers used in the treatment of infantile hemangioma and address their efficacy and safety. Methodology: Based on all the steps adopted, the guiding question defined was: "Is the use of beta-blockers in patients with infantile hemangioma, when compared to the use of placebo or other drugs, effective in resolving or reducing lesions?". Initially, 220 studies were found. After applying the search criteria, seven articles were chosen to compose the literature review. Results and discussion: it was observed that beta-blockers are widely used in the treatment of IHs, being mainly effective in the early and initial proliferative phases. The most commonly used beta-blocker is propranolol, but in cases of sensitivity or serious adverse events, timolol, atenolol, carteolol and betaxolol can be used, both in topical and oral presentation. Joint therapy with two beta-blockers has also been shown to be effective in resolving His. Conclusion: The use of beta-blockers in the treatment of infantile hemangioma is beneficial to patients, being safe and effective, and presenting little or no systemic side effects.

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Author Biographies

Rosangela Cristina Souza Abdala

Centro Universitário Claretiano.

Alexandre Teixeira do Amaral

Centro Universitário Claretiano.

Pedro Augusto Balista Canevarolo

Centro Universitário Claretiano.

Mirelly Dantas Caldeira Aeissami

Faculdade Atenas.

Natália Vasconcelos Carvalho

Universidade Professor Edson Antônio Velano - UNIFENAS.

Ana Flávia Fonseca de Oliveira

Universidade Professor Edson Antônio Velano - UNIFENAS.

Thiarles Ferreira da Silva

Universidade Professor Edson Antônio Velano - UNIFENAS.

Filipe Silva Borges de Oliveira

Universidade Professor Edson Antônio Velano - UNIFENAS.

Luiz Gabriel Gonçalves Cherain

Estudante do 7° período de medicina na Faculdade Atenas - Campus Passos.  Membro fundador da Liga Acadêmica de Neurologia e Neurocirurgia da Faculdade Atenas. Membro da Liga Acadêmica de Urgência e Emergência da Faculdade Atenas. Embaixador do programa BRAINterns, do Lenox Hill Hospital, NY - EUA. Membro estudante da Academia Europeia de Neurologia e da Sociedade Brasileira de Clínica Médica.

Wesley Ramires de Souza Liberato

Universidade Professor Edson Antônio Velano - UNIFENAS.

References

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Published

04/08/2023

How to Cite

Souza Abdala, R. C., Teixeira do Amaral, A., Balista Canevarolo, P. A., Dantas Caldeira Aeissami, M., Vasconcelos Carvalho, N., Fonseca de Oliveira, A. F., … Ramires de Souza Liberato, W. (2023). USE OF BETABLOCKERS IN THE TREATMENT OF INFANTILE HEMANGIOMA. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 4(8), e483731. https://doi.org/10.47820/recima21.v4i8.3731

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Vol. 4 No. 8 (2023): CLICK HERE TO ACCESS THE ARTICLES

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