ADVANCES IN PHARMACOLOGICAL THERAPY FOR URINARY TRACT INFECTIONS: A LITERATURE REVIEW
DOI:
https://doi.org/10.47820/recima21.v5i3.4995Keywords:
Urinary tract infections, pharmacological therapy, advances.Abstract
Introduction: Urinary tract infections (UTIs) represent a global challenge, impacting quality of life and generating significant costs. Antimicrobial resistance increases the complexity of conventional antibiotic treatment. The search for innovative therapies is crucial to tackling this problem. Objective: This review analyzes recent advances in pharmacological therapy for UTIs, highlighting new antimicrobial agents and non-antibiotic therapies. We also explore advanced diagnostics, multidisciplinary approaches and the impact of the COVID-19 pandemic on UTIs. Challenges in specific populations, ethical and economic considerations, as well as prevention strategies, urinary microbiota and precision medicine are discussed. Methods: We conducted a literature review of the last 15 years, including original studies and reviews. Inclusion criteria included new therapies, antimicrobial agents and advances in diagnosis. The search involved PubMed, Web of Science, Scopus and Google Scholar. The final sample comprised studies relevant to the pharmacological therapy of UTIs. Results and Discussion: Advances in new antimicrobial agents, non-antibiotic therapies and molecular diagnostics stand out. Multidisciplinary and collaborative strategies have shown benefits, while the COVID-19 pandemic has impacted treatment patterns. Conclusion: Despite progress, persistent challenges include antimicrobial resistance, ethical and economic issues. Investing in research, prevention strategies and precision medicine is crucial to optimize the clinical management of UTIs. This review highlights the continued need for innovation in the approach to UTIs, aiming to benefit individuals and global public health.
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