TREATMENT OF HELICOBACTER PYLORI-RELATED GASTRIC ULCER: SURGICAL AND CONSERVATIVE APPROACHES - A LITERATURE REVIEW
DOI:
https://doi.org/10.47820/recima21.v5i4.5103Keywords:
Gastric ulcer. Helicobacter pylori. Therapeutic approach. Surgical treatmentAbstract
Introduction: Helicobacter pylori-related gastric ulcer is a significant clinical condition marked by challenges such as antibiotic resistance and complications. Surgical and conservative therapeutic approaches play a crucial role in the management of this condition. Objective: This literature review seeks to address surgical and conservative approaches to the treatment of Helicobacter pylori-related gastric ulcers. Methods: A literature review was carried out using scientific databases such as PubMed, Web of Science, Scopus and Google Scholar, from 2004 to 2024. Original studies and reviews investigating therapeutic approaches, pathophysiology and quality of life related to gastric ulcer and H. pylori were included. Results and Discussion: The results and discussion emphasize the effectiveness of conservative therapeutic approaches, such as triple regimens, and the benefits of surgical ones, such as laparoscopic gastrectomy. Challenges such as antibiotic resistance, complications and adherence to treatment are also addressed, highlighting the importance of a multidisciplinary approach. Conclusion: An integrated, evidence-based approach is key to optimizing the management of H. pylori-related gastric ulcers. Areas for future research are highlighted, such as personalized therapies and strategies to overcome challenges such as antibiotic resistance and complications, with the aim of improving clinical outcomes and patients' quality of life.
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AKBULUT, Sezer et al. Is Helicobacter pylori eradication required after laparoscopic sleeve gastrectomy?. Videosurgery and Other Miniinvasive Techniques, v. 17, n. 4, p. 705-709, 2022. DOI: https://doi.org/10.5114/wiitm.2022.116418
BAI, Xiaofen et al. The impacts of probiotics in eradication therapy of Helicobacter pylori. Archives of Microbiology, v. 204, n. 12, p. 692, 2022. DOI: https://doi.org/10.1007/s00203-022-03314-w
CHIVU, Roxana Florentina et al. Helicobacter pylori Infection at Crossroads between Specialties. Chirurgia (Bucharest, Romania: 1990), v. 119, n. eCollection, p. 1-1, 2024. DOI: https://doi.org/10.21614/chirurgia.119.eC.2949
CHOI, Il Ju et al. Helicobacter pylori therapy for the prevention of metachronous gastric cancer. New England Journal of Medicine, v. 378, n. 12, p. 1085-1095, 2018. DOI: https://doi.org/10.1056/NEJMoa1708423
DU, Li-Jun et al. Helicobacter pylori eradication therapy for functional dyspepsia: systematic review and meta-analysis. World journal of gastroenterology, v. 22, n. 12, p. 3486, 2016. DOI: https://doi.org/10.3748/wjg.v22.i12.3486
FASHNER, Julia; GITU, Alfred C. Diagnosis and treatment of peptic ulcer disease and H. pylori infection. American family physician, v. 91, n. 4, p. 236-242, 2015.
FITZGERALD, Rebecca; SMITH, Sinéad M. An overview of Helicobacter pylori infection. Helicobacter pylori, p. 1-14, 2021. DOI: https://doi.org/10.1007/978-1-0716-1302-3_1
FORD, Alexander C. et al. Eradication therapy for peptic ulcer disease in Helicobacter pylori‐positive people. Cochrane Database of Systematic Reviews, n. 4, 2016. DOI: https://doi.org/10.1002/14651858.CD003840.pub5
GARZA-GONZÁLEZ, Elvira et al. A review of Helicobacter pylori diagnosis, treatment, and methods to detect eradication. World journal of gastroenterology: WJG, v. 20, n. 6, p. 1438, 2014. DOI: https://doi.org/10.3748/wjg.v20.i6.1438
GRAHAM, David Y. History of Helicobacter pylori, duodenal ulcer, gastric ulcer and gastric cancer. World Journal of Gastroenterology: WJG, v. 20, n. 18, p. 5191, 2014. DOI: https://doi.org/10.3748/wjg.v20.i18.5191
ISSEVER, Kubilay et al. Helicobacter Pylori and Celiac Disease Antibody Positivity Have a Higher Prevalence in Patients With Distal Gastrectomy: A Cross-Sectional Retrospective Study. Cureus, v. 15, n. 8, 2023. DOI: https://doi.org/10.7759/cureus.42976
KAVITT, Robert T. et al. Diagnosis and treatment of peptic ulcer disease. The American journal of medicine, v. 132, n. 4, p. 447-456, 2019. DOI: https://doi.org/10.1016/j.amjmed.2018.12.009
KIM, Tae Jun et al. A cohort study on Helicobacter pylori infection associated with nonalcoholic fatty liver disease. Journal of gastroenterology, v. 52, p. 1201-1210, 2017. DOI: https://doi.org/10.1007/s00535-017-1337-y
LEMOS, Fabian Fellipe Bueno et al. Effectiveness of Helicobacter pylori eradication in the treatment of early-stage gastric mucosa-associated lymphoid tissue lymphoma: An up-to-date meta-analysis. World Journal of Gastroenterology, v. 29, n. 14, p. 2202, 2023. DOI: https://doi.org/10.3748/wjg.v29.i14.2202
LIN, Yang-Sheng et al. Management of Helicobacter pylori infection after gastric surgery. World journal of gastroenterology: WJG, v. 20, n. 18, p. 5274, 2014. DOI: https://doi.org/10.3748/wjg.v20.i18.5274
MEDAKINA, Irina et al. Helicobacter pylori Antibiotic Resistance: Molecular Basis and Diagnostic Methods. International Journal of Molecular Sciences, v. 24, n. 11, p. 9433, 2023. DOI: https://doi.org/10.3390/ijms24119433
MIWA, Hiroto et al. Evidence-based clinical practice guidelines for functional dyspepsia 2021. Journal of Gastroenterology, v. 57, n. 2, p. 47-61, 2022. DOI: https://doi.org/10.1007/s00535-021-01843-7
O'CONNOR, Anthony et al. Review–treatment of Helicobacter pylori infection 2020. Helicobacter, v. 25, p. e12743, 2020. DOI: https://doi.org/10.1111/hel.12743
OTERO, William et al. Helicobacter pylori:¿ cómo se trata en el 2018?. Revista de Gastroenterología del Perú, v. 38, n. 1, p. 54-63, 2018.
REN, Shuai et al. Prevalence of Helicobacter pylori infection in China: A systematic review and meta‐analysis. Journal of gastroenterology and hepatology, v. 37, n. 3, p. 464-470, 2022. DOI: https://doi.org/10.1111/jgh.15751
SABBAGH, Parisa et al. Diagnostic methods for Helicobacter pylori infection: ideals, options, and limitations. European Journal of Clinical Microbiology & Infectious Diseases, v. 38, p. 55-66, 2019. DOI: https://doi.org/10.1007/s10096-018-3414-4
SANTIAGO, Silvana Barbosa et al. Resistência da Helicobacter pylori aos antibióticos utilizados em diferentes esquemas terapêuticos: uma revisão integrativa: Resistência da Helicobacter pylori aos antibióticos utilizados em diferentes esquemas terapêuticos. Clinical and Biomedical Research, v. 43, n. 2, 2023. DOI: https://doi.org/10.22491/2357-9730.125639
TSHIBANGU-KABAMBA, Evariste; YAMAOKA, Yoshio. Helicobacter pylori infection and antibiotic resistance—from biology to clinical implications. Nature Reviews Gastroenterology & Hepatology, v. 18, n. 9, p. 613-629, 2021. DOI: https://doi.org/10.1038/s41575-021-00449-x
WROBLEWSKI, Lydia E.; PEEK JR, Richard M.; WILSON, Keith T. Helicobacter pylori and gastric cancer: factors that modulate disease risk. Clinical microbiology reviews, v. 23, n. 4, p. 713-739, 2010. DOI: https://doi.org/10.1128/CMR.00011-10
YANG, Jyh-Chin; LU, Chien-Wei; LIN, Chun-Jung. Treatment of Helicobacter pylori infection: current status and future concepts. World journal of gastroenterology: WJG, v. 20, n. 18, p. 5283, 2014. DOI: https://doi.org/10.3748/wjg.v20.i18.5283
YIP, Hon Chi; TEOH, Anthony Yuen Bun. Importance of timely eradication of Helicobacter pylori to prevent peptic ulcer recurrence and gastric cancer. Gastrointestinal endoscopy, v. 88, n. 2, p. 251-252, 2018. DOI: https://doi.org/10.1016/j.gie.2018.03.016
YONEZAWA, Hideo et al. Biofilm formation by Helicobacter pylori and its involvement for antibiotic resistance. BioMed research international, v. 2015, 2015. DOI: https://doi.org/10.1155/2015/914791
ZAZADZE, R. et al. MEDICATIONS FOR ERADICATION OF HELICOBACTER PYLORI. Georgian Medical News, n. 322, p. 162-166, 2022.
ZHANG, Mengran; PANG, Mingge; ZHANG, Mei. Efficacy and safety of potassium-competitive acid blockers versus proton pump inhibitors as Helicobacter pylori eradication therapy: a meta-analysis of randomized clinical trials. Clinics, v. 77, p. 100058, 2022. DOI: https://doi.org/10.1016/j.clinsp.2022.100058
ZHANG, Yunzhan et al. The role of E-cadherin in Helicobacter pylori-related gastric diseases. Current Drug Metabolism, v. 20, n. 1, p. 23-28, 2019. DOI: https://doi.org/10.2174/1389200219666180625113010
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