INFECTIOUS AGENTS FOUND IN GASTROINTESTINAL BIOPSIES OF PATIENTS FROM A REFERENCE HOSPITAL IN INFECTOLOGY IN AMAZONAS
DOI:
https://doi.org/10.47820/recima21.v5i8.5517Keywords:
Gastrointestinal tract. Opportunistic infections. Endoscopy. Biopsy, Epidemiology. Acquired immunodeficiency syndrome.Abstract
The gastrointestinal tract is a frequent site of involvement in opportunistic infections. Many etiological agents are included and can be of bacterial, viral, fungal or parasitic origin. Objective: To analyze the infectious agents found in gastrointestinal biopsies. Methodology: Epidemiological, retrospective, cross-sectional study with a quantitative approach of information from biopsies of the gastrointestinal tract and histopathological examinations with clinical data from patients, existing in databases of the pathology laboratory of the reference hospital for infectology in Amazonas. Results: Information from 492 biopsy slides from patients with HIV was analyzed, 69.9% of which were from male patients and the majority (83.9%) also had a diagnosis of gastritis as an associated disease. Most of these samples (77.3%) had bacteria as the main etiological agent, followed by fungi ((32.4%), viruses (4.9%) and parasites (0.9%). The most common species was Helicobacter pylori (75%), Candida sp (15.7%), Istoplasma capsulatun (7.4%), Cytomegalovirus (2.5) and Herpevirus (2.5%). frequency was the stomach (80.69%) and esophagus (12.6%). Regarding clinical symptoms, 34.5% had diarrhea as the main symptom. Conclusion: Histopathological examination is extremely important for the diagnosis of gastrointestinal tract infections.
Downloads
References
Montalvo-Otivo R, et al. Evaluación de la diarrea crónica en pacientes con reciente diagnóstico de infección por VIH mediante el panel gastrointestinal FilmArray®. Revista de Gastroenterología de México. 2024;89(1):80-88. https://www.sciencedirect.com/science/article/pii/S0375090623000058 DOI: https://doi.org/10.1016/j.rgmx.2022.11.002
Motta CSL, et al. Sífilis e/ou HIV: perfil epidemiológico das gestantes infectadas num município da região serrana do estado do rio de janeiro, Brasil. 2018;01.
Almeida N, et al. Avaliação da imunidade celular do cd4 no combate ao vírus do HIV. Revista Saúde em Foco. 2018;(10):645–651. http://indicadores.aids.gov.br/
Brasil. Ministério da Saúde. Boletim Epidemiológico – AIDS e IST. Brasília: Ministério da Saúde; 2017. 64p.
Machiels JD, et al. Impact of the BioFire FilmArray gastrointestinal panel on patient care and infection control. PLoS One. 2020;15:e0228596, http://dx.doi. org/10.1371/journal.pone.0228596 DOI: https://doi.org/10.1371/journal.pone.0228596
Hitchcock M, et al. Low yield of FilmArray GI panel in hospitalized patients with diarrhea: An opportunity for diagnostic stewardship intervention. J Clin Microbiol. 2018;56:e01558---1617, http://dx.doi.org/10.1128/JCM. 01558-17 DOI: https://doi.org/10.1128/JCM.01558-17
Kreiniz N, et al et al. Shigalike toxin-producing Escherichia coli inducing diarrhea in patients with multiple myeloma diagnosed by BioFire PCR-Film Array. Acta Haematol. 2019;142:187-9. http://dx.doi.org/10.1159/000498906. DOI: https://doi.org/10.1159/000498906
Utami WS, et al et al. Cryptosporidium infection increases the risk for chronic diarrhea among people living with HIV in Southeast Asia: A systematic review and meta-analysis. Asia Pac J Public Health. 2020;32:8-18. http://dx.doi.org/10.1177/1010539519895422. DOI: https://doi.org/10.1177/1010539519895422
Santos JPV dos, et al. Principais achados e rendimento diagnóstico da broncofibroscopia de pacientes HIV positivos/AIDS atendidos na Universidade Federal do Triângulo Mineiro; 2019. https://bdtd.uftm.edu.br/handle/tede/681
Ciarlini NSC, et al. Parasitismo duodenal de Leishmania spp. em pacientes com coinfecção HIV/Leishmania. 2018. https://repositorio.ufc.br/handle/riufc/40448
De Medeiros FAF, et al. Espiroquetose intestinal como manifestação de sífilis em paciente vivendo com HIV. The Brazilian Journal of Infectious Diseases, 2022;26:101839. https://www.sciencedirect.com/science/article/pii/S1413867021003081 DOI: https://doi.org/10.1016/j.bjid.2021.101839
Araújo CG, et al. Histoplasmose gastrointestinal simulando doença de Crohn em paciente imunossuprimido: relato de caso. Revista Brasileira de Pesquisa em Saúde/Brazilian Journal of Health Research. 2024;26(supl_1):68-75. https://periodicos.ufes.br/rbps/article/view/44397/29952 DOI: https://doi.org/10.47456/rbps.v26isupl_1.44397
Ekeng BE, et al. Gastrointestinal Histoplasmo-sis: A Descriptive Review, 2001-2021. Life (Basel). 2023 Mar 3;13(3):689. DOI: https://doi.org/10.3390/life13030689
McCluskey SM, et al. Adherence, resistance, and viral suppression on dolutegravir in sub-Saharan Africa: implications for the TLD era. AIDS. 2021 Dec 15;35(Suppl 2):S127-S135. DOI: https://doi.org/10.1097/QAD.0000000000003082
Suárez-García I, et al. Cohort of the Spanish HIV/AIDS Research Network (CoRIS). Effectiveness and toler-ability of dolutegravir/lamivudine for the treatment of HIV-1 infection in clinical practice. J Antimicrob Chemother. 2023 Jun 1;78(6):1423-1432.
Cardoso MSE, et al. Diagnóstico de infecções oportunistas em trato gastrointestinal em paciente recém diagnosticado com aids: relato de um caso em paciente internado num serviço de referência de HIV/AIDS na cidade de SÃO PAULO. The Brazilian Journal of Infectious Diseases. 2022;26:101836. https://www.sciencedirect.com/science/article/pii/S1413867021003056 DOI: https://doi.org/10.1016/j.bjid.2021.101836
Ferreira TRL, et al. Sífilis intestinal em paciente imunodeprimidos e suas nuances no diagnóstico. The Brazilian Journal of Infectious Diseases. 2022;26:102559. https://www.sciencedirect.com/science/article/pii/S141386702200246X DOI: https://doi.org/10.1016/j.bjid.2022.102559
Tafarel JR, et al. Imunossuprimir ou não imunossuprimir? eis a questão. The Brazilian Journal of Infectious Diseases. 2022;26:101842. https://www.sciencedirect.com/science/article/pii/S1413867021003111 DOI: https://doi.org/10.1016/j.bjid.2021.101842
Pelandré AF, et al. Linfoma duodenal primário de células b em paciente com vírus da imunudoficiência humana: relato de caso. Arquivos Catarinenses de Medicina. 2021;50(2):372-377. https://revista.acm.org.br/index.php/arquivos/article/view/653
De Azambuja AP, et al. Diagnóstico de linfoma hepatoesplênico gama-delta em paciente imunossuprimido. Hematology, Transfusion and Cell Therapy. 2023;45:9. https://www.sciencedirect.com/science/article/pii/S2531137923000597 DOI: https://doi.org/10.1016/j.htct.2023.03.015
Silva MCG, et al. Tuberculose intestinal: um desafio diagnóstico num paciente com doença de Hodgkin. Hematology, Transfusion and Cell Therapy. 2021;43:S61-S62. https://www.sciencedirect.com/science/article/pii/S2531137921002522 DOI: https://doi.org/10.1016/j.htct.2021.10.105
Da Fonseca Marques ET, et al. Uma análise acerca das características da Doença Celíaca: revisão de literatura. Revista Eletrônica Acervo Médico. 2022;15:e10722-e10722. https://acervomais.com.br/index.php/medico/article/view/10722 DOI: https://doi.org/10.25248/reamed.e10722.2022
Downloads
Published
How to Cite
License
Copyright (c) 2024 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
![Creative Commons License](http://i.creativecommons.org/l/by/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution 4.0 International License.
Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.