CANNABIS USE IN DOGS WITH CHRONIC DISEASES: WHAT IS THE EVIDENCE?
DOI:
https://doi.org/10.47820/recima21.v3i9.1742Keywords:
explore the use of Cannabinoids in casesAbstract
Objective: The present study has as main objective to explore the use of Cannabinoids in cases of chronic diseases in dogs, analyzing its relevance, pharmacodynamics, therapeutic capacity and positive and negative effects in the treatment. Methods: A narrative review was conducted that investigated the production of knowledge about the use of Cannabis in dogs with chronic diseases and its evidence. The following databases were searched: LILACS, MEDLINE, PUBMED and SciELO, in the period from 2018 to 2022. The search terms used were: Cannabis, chronic pain, dogs, treatment and quality of life. Data collection took place in March 2022. Review: Cannabis is a plant belonging to the Cannabaceae family and has medicinal properties. In some countries, Cannabis and derivatives are used legally for medicinal purposes in humans. However, in Veterinary Medicine, research on its use is still in its early stages, due to the vast chemical diversity of its composition and actions on the physiological system of different animals. Therefore, there are few in vivo reports of Cannabis in animals, but its application as an analgesic and anticonvulsant has been shown to be relevant. There is interest in studying Cannabidiol, a derivative of the plant, as an analgesic in dogs, mainly because its neither additive nor hallucinogen. Final considerations: Given the above, it's important to seek knowledge about the use of cannabis in dogs with chronic pain, since it has analgesic action in this species, however, further study is needed to affirm the safety of its therapeutic application in these animals.
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BRUTLAG, Ahna; HOMMERDING, Holly. Toxicology of marijuana, synthetic cannabinoids, and cannabidiol in dogs and cats. Veterinary Clinics: Small Animal Practice, v. 48, n. 6, p. 1087-1102, 2018.
CINDY, H. J.; RUPASINGHE, HP Vasantha. Cannabidiol-based natural health products for companion animals: Recent advances in the management of anxiety, pain, and inflammation. Research in Veterinary Science, v. 140, p. 38-46, 2021.
DE BRIYNE, Nancy et al. Cannabis, Cannabidiol Oils and Tetrahydrocannabinol—What Do Veterinarians Need to Know?. Animals, v. 11, n. 3, p. 892, 2021.
DELLA ROCCA, Giorgia; DI SALVO, Alessandra. Hemp in veterinary medicine: from feed to drug. Frontiers in Veterinary Science, v. 7, p. 387, 2020.
GAMBLE, Lauri-Jo et al. Pharmacokinetics, safety, and clinical efficacy of cannabidiol treatment in osteoarthritic dogs. Frontiers in veterinary science, p. 165, 2018.
HAZZAH, Trina et al. Cannabis in veterinary medicine: a critical review. AHVMA, v. 61, p. 25, 2020.
KOGAN, Lori et al. US veterinarians' knowledge, experience, and perception regarding the use of cannabidiol for canine medical conditions. Frontiers in Veterinary Science, v. 5, p. 338, 2019.
NICHOLS, James M.; KAPLAN, Barbara LF. Immune responses regulated by cannabidiol. Cannabis and cannabinoid research, v. 5, n. 1, p. 12-31, 2020.
REPETTI, Cláudia Sampaio Fonseca et al. Perspectives in veterinary medicine on the use of cannabinoids as complementary palliative therapy for pain in cancer patients. Ciência Rural, v. 49, 2019.
RITTER, Sivan et al. Cannabis, One Health, and Veterinary Medicine: Cannabinoids’ Role in Public Health, Food Safety, and Translational Medicine. Rambam Maimonides Medical Journal, v. 11, n. 1, 2020.
VAUGHN, Dana; KULPA, Justyna; PAULIONIS, Lina. Preliminary investigation of the safety of escalating cannabinoid doses in healthy dogs. Frontiers in veterinary science, p. 51, 2020.
VOGT, Nadine A. et al. A survey of veterinary student attitudes concerning whether marijuana could have therapeutic value for animals. Plos one, v. 14, n. 7, p. e0219430, 2019.
VERRICO, Chris D. et al. A randomized, double-blind, placebo-controlled study of daily cannabidiol for the treatment of canine osteoarthritis pain. Pain, v. 161, n. 9, p. 2191, 2020.
WALLACE, Jean E. et al. Motivations and expectations for using cannabis products to treat pain in humans and dogs: a mixed methods study. Journal of cannabis research, v. 2, n. 1, p. 1-12, 2020.
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