3D BIOPRINTING OF CARDIOVASCULAR TISSUES
DOI:
https://doi.org/10.47820/recima21.v3i12.2409Keywords:
bioinks, innovation, Cardiovascular diseasesAbstract
Introduction: Cardiovascular disease continues to be the leading cause of morbidity and mortality worldwide, despite recent advances in cardiology and cardiac surgery. Recent advances have allowed three-dimensional (3D) printing technologies to be applied, creating a bioprinting field. The aim of this study is to investigate the efficacy, safety and applications of 3D bioprinted cardiovascular tissues in patients with heart disease. Methodology: The definite guide question was: "Is the use of bioprinted cardiovascular tissues in 3D effective and safe in patients with heart disease?". The search for articles occurred in the main databases. The research was carried out using the following descriptors: "bioprinting", "cardiovascular" combined with each other by Boolean operators. After the critical evaluation, a final sample of 4 studies was obtained. Results and discussion: It is possible to observe that there are several types of fabrics that can be bioprinted, each in its particularity and specific advantage. Final considerations: Therefore, it is concluded that the use of bioprinted cardiac tissues in 3D is promising and may change the current perspective and prognosis in patients with congenital diseases and acute cardiac lesions. However, efficacy and safety need to be tested in real models, and more studies are needed in the area.
Downloads
References
TASNIM, Nishat et al. 3D bioprinting stem cell derived tissues. Cellular and Molecular Bioengineering, v. 11, n. 4, p. 219-240, 2018.
ONG, Chin Siang et al. 3D bioprinting using stem cells. Pediatric research, v. 83, n. 1, p. 223-231, 2018.
KIM, Kyung Seob et al. Transplantation of 3D bio-printed cardiac mesh improves cardiac function and vessel formation via ANGPT1/Tie2 pathway in rats with acute myocardial infarction. Biofabrication, v. 13, n. 4, p. 045014, 2021.
SHIN, Yu Jung et al. 3D bioprinting of mechanically tuned bioinks derived from cardiac decellularized extracellular matrix. Acta Biomaterialia, v. 119, p. 75-88, 2021.
LUI, Cecillia et al. Mechanical stimulation enhances development of scaffold‐free, 3D‐printed, engineered heart tissue grafts. Journal of tissue engineering and regenerative medicine, v. 15, n. 5, p. 503-512, 2021.
ONG, Chin Siang et al. 3D and 4D bioprinting of the myocardium: current approaches, challenges, and future prospects. BioMed research international, v. 2018, 2018.
SOUZA, Marcela Tavares de; SILVA, Michelly Dias da; CARVALHO, Rachel de. Revisão integrativa: o que é e como fazer. Einstein (São Paulo), v. 8, p. 102-106, 2010.
MENDES, Karina Dal Sasso; SILVEIRA, Renata Cristina de Campos Pereira; GALVÃO, Cristina Maria. Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto & contexto-enfermagem, v. 17, p. 758-764, 2008.
Kawai Y, Tohyama S, Arai K, et al. Scaffold-Free Tubular Engineered Heart Tissue From Human Induced Pluripotent Stem Cells Using Bio-3D Printing Technology in vivo. Front Cardiovasc Med. 2022;8. doi:10.3389/FCVM.2021.806215
Bejleri D, Robeson MJ, Brown ME, et al. In vivo evaluation of bioprinted cardiac patches composed of cardiac-specific extracellular matrix and progenitor cells in a model of pediatric heart failure. Biomater Sci. 2022;10(2):444-456. doi:10.1039/D1BM01539G
Gaetani R, Feyen DAM, Verhage V, et al. Epicardial application of cardiac progenitor cells in a 3D-printed gelatin/hyaluronic acid patch preserves cardiac function after myocardial infarction. Biomaterials. 2015;61:339-348. doi:10.1016/j.biomaterials.2015.05.005
Downloads
Published
Issue
Section
Categories
License
Copyright (c) 2022 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
This work is licensed under a Creative Commons Attribution 4.0 International License.
Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.