PHARMACEUTICAL INTERVENTION IN CASES OF USE OF ACETYLSALICYTIC ACID IN PEDIATRICS

Abstract

Acetylsalicylic acid (AAS), popularly known as aspirin, is a drug of rapid absorption and immediate action, which is of the class (MIP), that is, non-prescription, sold in various forms and flavors, generating a preference for its exacerbated consumption. Its main indication is the symptomatic relief of headache, toothache, sore throat related to colds, dysmenorrhea, myalgia or arthralgia, low back pain and pain. The objective is to describe the importance of the role of the pharmacist in cases of the use of acetylsalicylic acid in pediatrics. This is a bibliographic review in the following databases: Online Scientific Electronic Library (SCIELO), in Latin American and Caribbean Literature on Health Sciences (LILACS) and in the Online System of Search and Analysis of Medical Literature (MEDLINE). AAS has its action against COX 1 and 2 enzymes, where it reduces the production of prostaglandins, which are extremely important as endogenous mediators of various physiological processes. Currently, AAS has the most famous use in cardiovascular disease and diabetes. Its inhibitory effect on platelet aggregation. It is concluded that AAS may be related to an increased risk of bleeding, and its long-term indiscriminate use can cause gastrointestinal disorders, attacking the entire digestive system (stomach, esophagus, large intestine, small intestine, colon, rectum and anus), as well as the organs that are part of digestion such as the liver where the drug is metabolized, pancreas and gallbladder.