THERAPEUTIC TREATMENT OF ROSACEA WITH THE USE OF BOTULINUM TOXIN

Abstract

Introduction: We can define Rosacea as a chronic inflammatory vascular disease, with remissions and exacerbations, which, even with an unknown cause, is known to be strongly influenced by psychological factors, such as stress, which can trigger the disease. The main clinical manifestation comprises multifacial erythema. Currently, scientific studies consider important the participation of a mite from the normal skin flora called Demodex folliculorum, and the bacteria Bacillus oleronius, which colonizes this fungus. Botulinum toxin is a protein produced by the bacteria Clostridium botulinum; bacterium is the cause of botulism, and it is believed that the action of this toxin blocks nerve signals from the brain to the muscle, causing generalized paralysis, considering ingestion of high doses. Objective: The objective of this work was to carry out a survey of bibliographic works involving The use of botulinum toxin therapeutically, but achieving clinical results in the treatment of diseases whose activation mechanism is still unknown, such as Rosacea. Methodology: The main methodology of this work is bibliographic review, based on the survey of bibliographic data, where relevant scientific studies were selected and used as reference in the construction of this review. The research was carried out using the following databases, on known and secure digital platforms, such as: Scientific Electronic Library Online (SciELO), Surgical and Cosmetic Dermatology and Google Scholar, in addition to other approved scientific articles and works.