RELATIONSHIP BETWEEN HYPEROXIA AND MORTALITY IN MECHANICALLY VENTILATED ADULTS
DOI:
https://doi.org/10.47820/recima21.v5i8.5473Keywords:
Oxygen. Hyperoxia. Oxygen. Critical Patient.Abstract
The aim of this study was to evaluate the relationship between hyperoxia and mortality in adults on mechanical ventilation. Methods: Articles were included in electronic databases: Pubmed, SciElo and MedLine. originals indexed in Portuguese and English, in the period between January 1, 2012 and December 31, 2022. Randomized controlled trials, retrospective and prospective cohorts that evaluated the relationship between oxygen therapy and clinical outcomes such as mortality in critically ill patients were selected. Results: The analyzed studies presented divergent results regarding the ideal concentration of oxygen to be administered in critically ill patients, with evidence supporting the hypothesis that supplemental oxygen administration may be beneficial, as well as evidence showing that excess oxygen may be harmful. Most studies point to the need for individualized treatment based on oxygen saturation monitoring and clinical evaluation of the patient. Conclusion: Although there is divergence of results in the literature, it is consensus that oxygen administration in critically ill patients should be individualized and based on clinical evaluation and oxygen saturation monitoring. The hypothesis that supplemental oxygen administration may be harmful is plausible, and the definition of the ideal concentration should be done with caution. There is a need for better designed and larger sample studies to more precisely define the impact of oxygen therapy in critically ill patients.
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