STUDY OF PULSE BOOSTER DRUG DELIVERY TECHNOLOGY MESOJECTGUN® AND ITS RESULTS IN SCALP REGION

Abstract

Traditional mesotherapy consists of the application of highly diluted pharmacological substances directly into the area to be treated through intradermal injections. However, injections have disadvantages such as pain, needle phobia, edema, erythema, and bruising. With technological advancements, a new modality of instrumental therapy using electrical currents as a physical vehicle for the transdermal application of active ingredients has been developed. The active ingredients cross the transdermal barrier without the need for injections through a combination of electrostimulation and microabrasion. Thus, this study aims to discuss the research and application of Pulse Booster Drug Delivery Mesojectgun Technology, which combines the technique of electroporation via microchips with the microabrasion technique for precise and painless delivery of active ingredients into the scalp skin through drug delivery, as well as its results in the scalp region. The methodology used was documentary and descriptive analysis through a case study involving four volunteers with confirmed clinical diagnoses of androgenic alopecia, telogen effluvium, and alopecia areata. The results showed success in increasing hair volume, thickening hair strands, and improving hair loss after treatment with Pulse Booster Drug Delivery Mesojectgun technology and the application of the active ingredients HCPR and Hair Cocktail Plus, to induce hair growth, inhibit the 5-ALPHA-REDUCTASE enzyme, and prevent hair loss.