CHARACTERIZATION OF CLINICAL MANIFESTATIONS OF PRADER-WILLI SYNDROME AND TREATMENTS: AN INTEGRATIVE LITERATURE REVIEW
DOI:
https://doi.org/10.47820/recima21.v3i3.1199Keywords:
Prader-Willi Syndrome, Clinical manifestations, TreatmentAbstract
Prader-Willi Prader-Willi syndrome (PWS) is a complex multisystem disorder characterized by several clinical manifestations, including intellectual disability, infantile lethargy, and hypotonia, with subsequent impairment in motor development. The objective of the research was, therefore, to analyze the scientific productions about the clinical manifestations and treatments used for Prader-Willi syndrome. The present study is an integrative, quantitative and exploratory literature review in the online databases: LILACS, PubMed and Scielo. The search for the material was carried out using the PICo strategy. Data analysis was performed through a detailed reading of the content of articles categorized by pre-established inclusion and exclusion criteria. A total of 85 publications were obtained and after filtering applying the criteria, 10 publications were refined according to the objectives of the study, distributed in different journals and subdivided into two discursive categories, one that addresses the clinical manifestations and the other the treatments of the disease in question. Clinical manifestations are usually hypotonia, eating disorders and delay in their growth process from birth, but more studies are needed to corroborate the benefits of the indicated therapies and decrease the impacts of clinical manifestations in the life of the carrier.
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