HIGH-FREQUENCY OSCILLATORY VENTILATION IN PREMATURE NEWBORN
DOI:
https://doi.org/10.47820/recima21.v4i11.4266Keywords:
High frequency ventilation, Neonates, Neonatal intensive care unitAbstract
Introduction: Premature newborns with respiratory dysfunctions are often submitted to mechanical ventilation, which is essential in the management of these patients, but can induce pulmonary lesions. To reduce this risk, High Frequency Oscillatory Mechanical Ventilation (HFOV) has been used as a safer ventilatory strategy when compared to conventional modes. Method: Integrative review of randomized clinical trials with the main outcome analysis of the effects of HFOV in comparison with conventional ventilatory modes in preterm infants born before 37 weeks. Results: The 23 articles included in this study suggest that HFOV decreases the risk of lung injury and exogenous surfactant use, increases oxygenation area, presents faster improvement of hypoxemia, and reduces the time patients are on mechanical ventilation and oxygen therapy. Conclusion: The main limitation lies in the small sample size of most studies, although it is possible to assume that HFOV is a safe and effective mode, which presents favorable results when compared to other ventilatory modes. For a more specific analysis, further studies on the incidence of intracranial hemorrhage and its use in newborns with congenital heart disease would be needed.
Downloads
References
Bauer K, Buschkamp S, Marcinkowski M, Kössel H, Thome U, Versmold HT. Postnatal changes of extracellular volume, atrial natriuretic factor, and diuresis in a randomized controlled trial of high-frequency oscillatory ventilation versus intermittent positive-pressure ventilation in premature infants <30 weeks gestation. Crit Care Med. 2000 Jun;28(6):2064-8. doi: 10.1097/00003246-200006000-00066. PMID: 10890665.
Chen L, Wang L, Ma J, Feng Z, Li J, Shi Y. Ventilação oscilatória nasal de alta frequência em bebês prematuros com síndrome do desconforto respiratório e SDRA após extubação: um ensaio clínico randomizado e controlado. Peito. 2019 Abr;155(4):740-748. DOI: 10.1016/j.chest.2019.01.014. PMID: 30955572.
Dani C, Bertini G, Pezzati M, Filippi L, Pratesi S, Caviglioli C, Rubaltelli FF. Effects of pressure support ventilation plus volume guarantee vs. high-frequency oscillatory ventilation on lung inflammation in preterm infants. Pediatr Pulmonol. 2006
Gerstmann DR, Minton SD, Stoddard RA, Meredith KS, Mónaco F, Bertrand JM, Battisti O, Langhendries JP, François A, Clark RH. Estudo multicêntrico de ventilação oscilatória de alta frequência precoce Provo: melhora do desfecho pulmonar e clínico na síndrome do desconforto respiratório. Pediatria. 1996 Dez;98(6 Pt 1):1044-57. PMID: 8951252.
Gerstmann DR, Wood K, Miller A, Steffen M, Ogden B, Stoddard RA, Minton SD. Pediatria. 2001 Set;108(3):617-23. DOI: 10.1542/peds.108.3.617. PMID: 11533327.
Greenough A, Limb E, Marlow N, Peacock JL, Calvert S. Radiological outcome of very prematurely born infants randomised to high frequency oscillatory or conventional ventilation. Eur J Pediatr. 2004 Nov;163(11):671-4. doi: 10.1007/s00431-004-1526-6. Epub 2004 Aug 12. PMID: 15309626.
Hofhuis W, Huysman MW, van der Wiel EC, Holland WP, Hop WC, Brinkhorst G, de Jongste JC, Merkus PJ. Worsening of V'maxFRC in infants with chronic lung disease in the first year of life: a more favorable outcome after high-frequency oscillation ventilation. Am J Respir Crit Care Med. 2002 Dec 15;166(12 Pt 1):1539-43. doi: 10.1164/rccm.2202046. PMID: 12471071.
Lista G, Castoldi F, Bianchi S, Battaglioli M, Cavigioli F, Bosoni MA. Volume guarantee versus high-frequency ventilation: lung inflammation in preterm infants. Arch Dis Child Fetal Neonatal Ed. 2008 Jul;93(4):F252-6. doi: 10.1136/adc.2006.112102. Epub 2007 Apr 3. PMID: 17405870.
Lista G, Castoldi F, Bianchi S, Lupo E, Cavigioli F, Farolfi A, Bersanini C, Ferrerio E. Lung function and respiratory health at school age in ventilated very low birth weight infants. Indian J Pediatr. 2014 Mar;81(3):275-8. doi: 10.1007/s12098-013-1129-1. Epub 2013 Jul 19. PMID: 23868538.
Liu CQ, Cui Z, Xia YF, Ma L, Fan LL. [Randomized controlled study of targeted tidal volume ventilation for treatment of severe neonatal respiratory distress syndrome]. Zhongguo Dang Dai Er Ke Za Zhi. 2011 Sep;13(9):696-9. Chinese. PMID: 21924013.
Marlow N, Greenough A, Peacock JL, Marston L, Limb ES, Johnson AH, Calvert SA. Randomised trial of high frequency oscillatory ventilation or conventional ventilation in babies of gestational age 28 weeks or less: respiratory and neurological outcomes at 2 years. Arch Dis Child Fetal Neonatal Ed. 2006 Sep;91(5):F320-6. doi: 10.1136/adc.2005.079632. Epub 2006 May 11. PMID: 16690640; PMCID: PMC2672829.
Merchak A, Janssen DJ, Bohlin K, Patterson BW, Zimmermann LJ, Carnielli VP, Hamvas A. O metabolismo endógeno do surfactante pulmonar não é afetado pelo modo de ventilação em prematuros com síndrome do desconforto respiratório. J Pediatr. 2002 Jun;140(6):693-8. DOI: 10.1067/mpd.2002.124320. PMID: 12072872.
Osborn DA, Evans N. Randomized trial of high-frequency oscillatory ventilation versus conventional ventilation: effect on systemic blood flow in very preterm infants. J Pediatr. 2003 Aug;143(2):192-8. doi: 10.1067/S0022-3476(03)00359-7. PMID: 12970631.
Plavka R, Kopecký P, Sebron V, Svihovec P, Zlatohlávková B, Janus V. A prospective randomized comparison of conventional mechanical ventilation and very early high frequency oscillatory ventilation in extremely premature newborns with respiratory distress syndrome. Intensive Care Med. 1999 Jan;25(1):68-75. doi: 10.1007/s001340050789. PMID: 10051081.
Prashanth GP, Malik GK, Singh SN. Elective high-frequency oscillatory ventilation in preterm neonates: a preliminary investigation in a developing country. Paediatr Int Child Health. 2012 May;32(2):102-6. doi: 10.1179/2046905512Y.0000000003. PMID: 22595219.
Rettwitz-Volk W, Veldman A, Roth B, Vierzig A, Kachel W, Varnholt V, Schlösser R, von Loewenich V. Estudo prospectivo, randomizado e multicêntrico sobre ventilação oscilatória de alta frequência comparada à ventilação convencional em prematuros com síndrome do desconforto respiratório recebendo surfactante. J Pediatr. 1998 Fev;132(2):249-54. DOI: 10.1016/s0022-3476(98)70440-8. PMID: 9506636.
Sarafidis K, Stathopoulou T, Agakidou E, Taparkou A, Soubasi V, Diamanti E, Drossou V. Comparable effect of conventional ventilation versus early high-frequency oscillation on serum CC16 and IL-6 levels in preterm neonates. J Perinatol. 2011 Feb;31(2):104-11. doi: 10.1038/jp.2010.78. Epub 2010 Jul 29. PMID: 20671716.
Seth S, Saha B, Saha AK, Mukherjee S, Hazra A. Nasal HFOV versus nasal IPPV as a post-extubation respiratory support in preterm infants-a randomised controlled trial. Eur J Pediatr. 2021 Oct;180(10):3151-3160. doi: 10.1007/s00431-021-04084-1. Epub 2021 Apr 23. PMID: 33890156; PMCID: PMC8062142.
Singh SN, Malik GK, Prashanth GP, Singh A, Kumar M. High frequency oscillatory ventilation versus synchronized intermittent mandatory ventilation in preterm neonates with hyaline membrane disease: a randomized controlled trial. Indian Pediatr. 2012 May;49(5):405-8. doi: 10.1007/s13312-012-0084-7. PMID: 22700666.
Sun H, Cheng R, Kang W, Xiong H, Zhou C, Zhang Y, Wang X, Zhu C. High-frequency oscillatory ventilation versus synchronized intermittent mandatory ventilation plus pressure support in preterm infants with severe respiratory distress syndrome. Respir Care. 2014 Feb;59(2):159-69. doi: 10.4187/respcare.02382. Epub 2013 Jun 13. PMID: 23764865.
Thome U, Götze-Speer B, Speer CP, Pohlandt F. Comparison of pulmonary inflammatory mediators in preterm infants treated with intermittent positive pressure ventilation or high frequency oscillatory ventilation. Pediatr Res. 1998 Sep;44(3):330-7. doi: 10.1203/00006450-199809000-00011. PMID: 9727709.
Vento G, Matassa PG, Ameglio F, Capoluongo E, Zecca E, Tortorolo L, Martelli M, Romagnoli C. HFOV in premature neonates: effects on pulmonary mechanics and epithelial lining fluid cytokines. A randomized controlled trial. Intensive Care Med. 2005 Mar;31(3):463-70. doi: 10.1007/s00134-005-2556-x. Epub 2005 Feb 17. PMID: ,15717206.
Zivanovic S, Peacock J, Alcazar-Paris M, Lo JW, Lunt A, Marlow N, Calvert S, Greenough A. Late outcomes of a randomized trial of high-frequency oscillation in neonates. N Engl J Med. 2014 Mar 20;370(12):1121-1130. doi: 10.1056/NEJMoa1309220. PMID: 24645944; PMCID: PMC4090580.
Downloads
Published
How to Cite
License
Copyright (c) 2023 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
This work is licensed under a Creative Commons Attribution 4.0 International License.
Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.
