SCIENCE AND ENDODONTICS FOR PEDIATRIC DENTISTRY: A NARRATIVE REVIEW

Authors

  • Irving Pablo Fernandez Calle https://orcid.org/0009-0002-6593-0658
  • Jenny Claudia Apaza Cayo
  • Carla Barrios Malaga
  • Eva Fernández Coca
  • Marivel Irene Condori Escobar
  • Edwin Macias Limachi Red Coordinadora de Medicina Dental 6, Centro de Salud de Achocalla, Achocalla, La Paz, Bolivia.
  • Abigail Marisol Vargas Ticona

DOI:

https://doi.org/10.47820/recima21.v5i8.5563

Keywords:

Endodontics, pediatric dentistry, LSTR.

Abstract

The field of endodontics is constantly evolving and research focuses on the development of innovative techniques and materials to protect periapical tissues. The LSTR (Lesion and Tissue Styling and Repair) technique has shown promise in removing lesions and repairing dental tissues, but its effectiveness and safety remain unclear. This study aims to evaluate the effectiveness of LSTR in long-term follow-up in the treatment of partial or total pulp lesions in primary teeth, comparing it with other endodontic techniques. The methodology was an electronic search in the PubMed, LILACS and Scopus databases of publications in English from the beginning of 2010 to July 15, 2024, of which 20 articles referring to the topic were selected. Results gave us to understand how an inflammatory and repair process begins in the dental pulp, antibiotics do not participate in these stages and other traditional non-cytotoxic substances, biological materials do form part of the formation and activation of regeneration and revascularization mediators. by having activity with stem cells and scaffold formation. Conclusion: SHED, DPSC, SCAP and PDLSC stem cells have also been mentioned as promising in regenerative medicine and tissue engineering therapies. It is also described that the use of biomaterials should be the new therapy to continue based on scientific evidence for the treatment of pulp therapies in pediatric dentistry that seek pulp regeneration or revascularization.

Downloads

Download data is not yet available.

Author Biographies

Irving Pablo Fernandez Calle

Pursarte PhD in Dental Sciences.

Master's Degree in Orthodontics.

Master's Degree in Clinical Pharmacology.

Specialty in Clinical Endodontics.

Diploma in Dental Pharmacology.

Diploma in General Pharmacology.

Diploma in Pharmacology and Pharmaceutical Care.

Diploma in Higher Education.

Diploma in Higher Education by Competencies.

Teacher, Master's Degree in Orthodontics, Technical University of Oruro, La Paz Sub-Branch.

Teacher and head of clinics, Specialty in endodontics, Technical University of Oruro, La Paz Sub-Branch.

Teacher and head of clinics, Diploma in endodontics, Public University of El Alto.

Teacher, Specialty in endodontics, National University "Siglo XX".

General Manager, Titanium Dental Clinic, Oruro, Bolivia.

Jenny Claudia Apaza Cayo

Specialty in Pediatric Dentistry.

Dentist, Private Dental Health Clinic, El Alto - La Paz, Bolivia.

Carla Barrios Malaga

Cursarte Specialty in Clinical Endodontics.

Diploma in Pediatric Dentistry.

Diploma in Endodontics.

Dentist, Private Clinic, Oruro, Bolivia.

Eva Fernández Coca

Pursarte Master's Degree in Pediatric Dentistry.

Specialist in Oral Surgery.

Diploma in Maxillofacial Imaging.

Diploma in higher education.

Specialist in Oral Surgery, Private Clinic, Llallagua, Bolivia.

Marivel Irene Condori Escobar

Master's Degree in Public Health.

Master's Degree in Orthodontics.

Municipal Head of Dentistry, Municipality of Viacha, Ministry of Health and Sports.

Dentist, Comprehensive Health Center, Viacha- La Paz, Bolivia.

Edwin Macias Limachi, Red Coordinadora de Medicina Dental 6, Centro de Salud de Achocalla, Achocalla, La Paz, Bolivia.

Clinical Specialty in Pediatric Dentistry.

Cursarte Specialty in Clinical Endodontics.

Diploma in Dentistry for Babies and Patients with Disabilities.

Diploma in higher education.

Diploma in Safci residency.

Coordinator of Dentistry, Network 6, municipality of Achocalla, La Paz Headquarters.

Dentist, Health Center with Hospitalization, Achocalla- La Paz, Bolivia.

Abigail Marisol Vargas Ticona

Master's Degree in Endodontics.

Diploma in Operative and Aesthetic Dentistry.

Diploma in Higher Education.

Diploma in Higher Education in Stomatology.

Undergraduate teacher, University of Aquino Bolivia, La Paz Bolivia.

Postgraduate teacher in Endodontics, Public University of El Alto.

Postgraduate teacher in Endodontics, National University "Siglo XX".

References

AGARWAL, S. R.; BENDGUDE, V. D.; KAKODKAR, P. Evaluation of Success Rate of Lesion Sterilization and Tissue Repair Compared to Vitapex in Pulpally Involved Primary Teeth: A Systematic Review. Journal of Conservative Dentistry: JCD, v. 22, n. 6, p. 510, 2019. https://doi.org/10.4103/JCD.JCD_76_20 DOI: https://doi.org/10.4103/JCD.JCD_76_20

BADAWY, S.; YANG, Y. Q.; LIU, Y.; MARAWAN, M. A.; ARES, I.; MARTINEZ, M. A.; MARTÍNEZ-LARRAÑAGA, M. R.; WANG, X.; ANADÓN, A.; MARTÍNEZ, M. Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism. Critical Reviews in Toxicology, v. 51, n. 9, p. 754–787, 2021. https://doi.org/10.1080/10408444.2021.2024496 DOI: https://doi.org/10.1080/10408444.2021.2024496

CASTRO, M.; LIMA, M.; LIMA, C.; MOURA, M.; MOURA, J.; MOURA, L. Lesion sterilization and tissue repair with chloramphenicol, tetracyline, zinc oxide/eugenol paste versus conventional pulpectomy: A 36-month randomized controlled trial. International Journal of Paediatric Dentistry, v. 33, n. 4, p. 335–345, 2023. https://doi.org/10.1111/IPD.13056 DOI: https://doi.org/10.1111/ipd.13056

CINTRA, L. T. A.; GOMES, M. S.; DA SILVA, C. C.; FARIA, F. D.; BENETTI, F.; COSME-SILVA, L.; SAMUEL, R. O.; PINHEIRO, T. N.; ESTRELA, C.; GONZÁLEZ, A. C.; SEGURA-EGEA, J. J. Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions. Odontology, v. 109, n. 4, p. 741–769, 2021. https://doi.org/10.1007/S10266-021-00636-X DOI: https://doi.org/10.1007/s10266-021-00636-x

DONG, X.; XU, X. Bioceramics in Endodontics: Updates and Future Perspectives. Bioengineering (Basel, Switzerland), v. 10, n. 3, 2023. https://doi.org/10.3390/BIOENGINEERING10030354 DOI: https://doi.org/10.3390/bioengineering10030354

DUARTE, M. L.; PIRES, P. M.; FERREIRA, D. M.; PINTOR, A. V. B.; DE ALMEIDA NEVES, A.; MAIA, L. C.; PRIMO, L. G. Is there evidence for the use of lesion sterilization and tissue repair therapy in the endodontic treatment of primary teeth? A systematic review and meta-analyses. Clinical Oral Investigations, v. 24, n. 9, p. 2959–2972, 2020. https://doi.org/10.1007/S00784-020-03415-0 DOI: https://doi.org/10.1007/s00784-020-03415-0

FIGUEROA-BANDA, R. A.; FIGUEROA-CASTELLANOS, K. F.; CHÁVEZ-OBLITAS, E. A.; GUILLEN-NUÑEZ, M. E.; AYQUI-CUEVA, F.; DEL-CARPIO-M, B. A.; BELLIDO-VALLEJO, K. L.; GÓMEZ, B. Theoretical Study at the Molecular Mechanics Level of the Interaction of Tetracycline and Chloramphenicol with the Antibiotic Receptors Present in Enterococcus faecalis (Q839F7) and Streptococcus mutans (Q8DS20). Antibiotics (Basel, Switzerland), v. 11, n. 11, 2022. https://doi.org/10.3390/ANTIBIOTICS11111640 DOI: https://doi.org/10.3390/antibiotics11111640

GARROCHO-RANGEL, A.; JALOMO-ÁVILA, C.; ROSALES-BERBER, M. Á.; POZOS-GUILLÉN, A. Lesion Sterilization Tissue Repair (LSTR) Approach of Non-Vital Primary Molars with A Chloramphenicol-Tetracycline-ZOE Antibiotic Paste: A Scoping Review. The Journal of Clinical Pediatric Dentistry, v. 45, n. 6, p. 369–375, 2021. https://doi.org/10.17796/1053-4625-45.6.1 DOI: https://doi.org/10.17796/1053-4625-45.6.1

GOMES, B. P. F. A.; AVEIRO, E.; KISHEN, A. Irrigants and irrigation activation systems in Endodontics. Brazilian Dental Journal, v. 34, n. 4, p. 1–33, 2023. https://doi.org/10.1590/0103-6440202305577 DOI: https://doi.org/10.1590/0103-6440202305577

JESKE, A. H. Contemporary dental pharmacology. [S. l.: s. n.], 2024. Vol. 2. https://books.google.com/books/about/Contemporary_Dental_Pharmacology.html?hl=es&id=IdFx0AEACAAJ

MANES URIBE, C.; RESTREPO, M.; DIEGO MEJÍA, J. Técnica LSTR con pasta CTZ para el tratamiento de la necrosis pulpar en molares primarios. Reporte de caso. Revista de Odontopediatría Latinoamericana, v. 13, 2023. https://doi.org/10.47990/ALOP.V13I.568 DOI: https://doi.org/10.47990/alop.v13i.568

MIURA, C. A. S.; SÁ, M. S.; LIMA, R. S.; MACHADO, M. A. A. M.; TELLES, P. D. S. Avaliação da toxicidade de materiais endodônticos em células-tronco da polpa dentária. ROBRAC, 2010. http://files.bvs.br/upload/S/0104-7914/2010/v19n50/a1547.pdf

RETAMOZO, B.; SHABAHANG, S.; JOHNSON, N.; APRECIO, R. M.; TORABINEJAD, M. Minimum contact time and concentration of sodium hypochlorite required to eliminate Enterococcus faecalis. Journal of Endodontics, v. 36, n. 3, p. 520–523, 2010. https://doi.org/10.1016/J.JOEN.2009.12.005 DOI: https://doi.org/10.1016/j.joen.2009.12.005

ROMERO-MIGUEL, D.; LAMANNA-RAMA, N.; CASQUERO-VEIGA, M.; GÓMEZ-RANGEL, V., DESCO, M.; SOTO-MONTENEGRO, M. L. Minocycline in neurodegenerative and psychiatric diseases: An update. European Journal of Neurology, v. 28, n. 3, p. 1056–1081, 2021. https://doi.org/10.1111/ENE.14642 DOI: https://doi.org/10.1111/ene.14642

SAIN, S. J. R. S. A.; GEORGE, S.; ISSAC, J. S.; JOHN, S. A. Lesion Sterilization and Tissue Repair-Current Concepts and Practices. International Journal of Clinical Pediatric Dentistry, v. 11, n. 5, p. 446–450, 2018. https://doi.org/10.5005/JP-JOURNALS-10005-1555 DOI: https://doi.org/10.5005/jp-journals-10005-1555

SCHAFFER, S. D.; HUTCHISON, C. A.; ROUCHON, C. N.; MDLULI, N. V.; WEINSTEIN, A. J.; MCDANIEL, D.; FRANK, K. L. Diverse Enterococcus faecalis strains show heterogeneity in biofilm properties. Research in Microbiology, v. 174, n. 1–2, p. 103986, 2023. https://doi.org/10.1016/J.RESMIC.2022.103986 DOI: https://doi.org/10.1016/j.resmic.2022.103986

SEQUEIRA, D. B.; DIOGO, P.; GOMES, B. P. F. A.; PEÇA, J.; SANTOS, J. M. M. Scaffolds for Dentin-Pulp Complex Regeneration. Medicina (Kaunas, Lithuania), v. 60, n. 1, 2023. https://doi.org/10.3390/MEDICINA60010007 DOI: https://doi.org/10.3390/medicina60010007

SHANKAR, K.; RAMKUMAR, H.; DHAKSHINAMOORTHY, S.; PAULINDRARAJ, S.; JAYAKARAN, T. G.; BOMMAREDDY, C. S. Comparison of Modified Triple Antibiotic Paste in Two Concentrations for Lesion Sterilization and Tissue Repair in Primary Molars: An In Vivo Interventional Randomized Clinical Trial. International Journal of Clinical Pediatric Dentistry, v. 14, n. 3, p. 388–392, 2021. https://doi.org/10.5005/JP-JOURNALS-10005-1951 DOI: https://doi.org/10.5005/jp-journals-10005-1951

SHARIATI, A.; ARSHADI, M.; KHOSROJERDI, M. A.; ABEDINZADEH, M.; GANJALISHAHI, M.; MALEKI, A.; HEIDARY, M.; KHOSHNOOD, S. The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic. Frontiers in Public Health, v. 10, 2022. https://doi.org/10.3389/FPUBH.2022.1025633 DOI: https://doi.org/10.3389/fpubh.2022.1025633

SHI, X.; MAO, J.; LIU, Y. Pulp stem cells derived from human permanent and deciduous teeth: Biological characteristics and therapeutic applications. Stem Cells Translational Medicine, v. 9, n. 4, p. 445–464, 2020. https://doi.org/10.1002/SCTM.19-0398 DOI: https://doi.org/10.1002/sctm.19-0398

SINGH, K.; REDDY, A.; ARYA, A.; SRIDHAR, V.; RANJAN, M.; BULBULE, N. Lesion Sterilization Tissue Repair: A Review. Journal of Pharmacy & Bioallied Sciences, v. 16, n. Suppl 1, p. S75–S77, 2024. https://doi.org/10.4103/JPBS.JPBS_411_23 DOI: https://doi.org/10.4103/jpbs.jpbs_411_23

SINGH, S.; KHANNA, D.; KALRA, S. Minocycline and Doxycycline: More Than Antibiotics. Current Molecular Pharmacology, v. 14, n. 6, p. 1046–1065, 2021. https://doi.org/10.2174/1874467214666210210122628 DOI: https://doi.org/10.2174/1874467214666210210122628

SMILACK, J. D. Tetraciclinas, sulfamidas y metronidazol. Mayo Clinic Proceedings, v. 74, n. 7, p. 727–729, 1999. https://doi.org/10.4065/74.7.727 DOI: https://doi.org/10.4065/74.7.727

SONG, W.; LI, S.; TANG, Q.; CHEN, L.; YUAN, Z. In vitro biocompatibility and bioactivity of calcium silicate based bioceramics in endodontics (Review). International Journal of Molecular Medicine, v. 48, n. 1, 2021. https://doi.org/10.3892/IJMM.2021.4961 DOI: https://doi.org/10.3892/ijmm.2021.4961

UREÑA, J. L. Microbiología oral. Libro, v. 3, p. 49–58, apr. 2002. https://books.google.com/books/about/Microbiologia_oral_2_Ed.html?hl=es&id=yYaGAAAACAAJ

XIE, Z.; SHEN, Z.; ZHAN, P.; YANG, J.; HUANG, Q.; HUANG, S.; CHEN, L.; LIN, Z. Functional Dental Pulp Regeneration: Basic Research and Clinical Translation. International Journal of Molecular Sciences, v. 22, n. 16, 2021. https://doi.org/10.3390/IJMS22168991 DOI: https://doi.org/10.3390/ijms22168991

ZAKY, S. H.; SHEHABELDIN, M.; RAY, H.; SFEIR, C. The role of inflammation modulation in dental pulp regeneration. European Cells & Materials, v. 41, p. 184–193, 2021. https://doi.org/10.22203/ECM.V041A13 DOI: https://doi.org/10.22203/eCM.v041a13

ZOU, J.; MAO, J.; SHI, X. Influencing factors of pulp-dentin complex regeneration and related biological strategies. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences, v. 51, n. 3, p. 350–361, 2022. https://doi.org/10.3724/ZDXBYXB-2022-0046 DOI: https://doi.org/10.3724/zdxbyxb-2022-0046

Downloads

Published

05/08/2024

How to Cite

Fernandez Calle, I. P., Apaza Cayo, J. C., Barrios Malaga, C., Fernández Coca, E., Condori Escobar, M. I., Macias Limachi, E., & Vargas Ticona, A. M. (2024). SCIENCE AND ENDODONTICS FOR PEDIATRIC DENTISTRY: A NARRATIVE REVIEW. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 5(8), e585563. https://doi.org/10.47820/recima21.v5i8.5563

Issue

Vol. 5 No. 8 (2024): CLICK HERE TO ACCESS THE ARTICLES

Section

ARTIGOS

Categories

License

Copyright (c) 2024 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores  e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.