ÔMEGA-3 E ASPIRINA COMO ADJUVANTES NO TRATAMENTO PERIODONTAL: REVISÃO DE LITERATURA

Autores

DOI:

https://doi.org/10.47820/recima21.v3i5.1295

Palavras-chave:

Ácidos graxos poli-insaturados, ácido acetilsalicílico, tratamento periodontal

Resumo

Estudos sobre os efeitos de metabólitos das lipoxinas (ácido araquidônico) e de ácidos graxos poli-insaturados do ômega-3 (ω-3) em associação aos efeitos de potencialização do ácido acetilsalicílico (ASA) na modulação e resolução inflamatória da doença periodontal, evidenciaram resultados benéficos como terapia adjuvante ao tratamento da doença periodontal. O presente estudo se propõe a revisar a literatura atual sobre os efeitos do ω-3 e sua combinação com ASA no tratamento da doença periodontal. Estudos clínicos randomizados controlados por placebo de desenhos paralelos e duplo-cegos foram utilizados como base literária para essa revisão de literatura. Os dados obtidos demonstram melhorias nos parâmetros clínicos periodontais, na diminuição dos níveis de biomarcadores pró-inflamatórios e na modulação e resolução da resposta inflamatória da doença periodontal, evidenciando uma favorável intervenção na condição inflamatória. Nota-se que a terapia de imunomodulação do hospedeiro com ω-3 demonstra benefícios nos parâmetros clínicos e inflamatórios de acordo com a literatura atual.

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Biografia do Autor

Rafael Nascimento de Brito Silva

Graduado em Odontologia pela Universidade Guarulhos. Atualmente, é mestrando em periodontia no programa de pós-graduação da Universidade Guarulhos.

Nidia Castro dos Santos

Dra. Castro dos Santos completou sua graduação em Odontologia na Universidade Estadual Paulista (UNESP) em São José dos Campos. É especialista em Periodontia. Possui mestrado em Microbiologia e Imunologia e doutorado em Periodontia pela UNESP. Realizou estágio de doutoramento no Forsyth Institute (Estados Unidos), no Centro de Pesquisa Clínica e Translacional, e pós-doutorado em Periodontia na Universidade Guarulhos. Atualmente é docente permanente do Programa de Pós-graduação em Odontologia na Universidade Guarulhos.

Magda Feres

Dra. Feres é periodontista (especialização e mestrado), Doutora em Biologia Oral pela Universidade de Harvard (EUA) e Pós-doutora em Microbiologia pelo Forsyth Institute (EUA). Ela é a coordenadora do Programa de Pós-Graduação em Odontologia da Universidade Guarulhos (único programa em Universidade particular com nota de excelência da CAPES) e Associate Professor do Forsyth.

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Queiroz Tavares R, Nogueira de Figueiredo M, Bustillos Torrez W, Fernandes Plutarco Nogueira C, Ferrari Roberto A, Rossit Silva Kiausinis KM, Feres M, Retamal-Valdes B. USO DE PROBIÓTICOS SISTÊMICOS NO TRATAMENTO PERIODONTAL NÃO CIRÚRGICO: REVISÃO NARRATIVA DA LITERATURA. RECIMA21 [Internet]. 12º de novembro de 2020 [citado 21º de setembro de 2021];1(2):280-30. Disponível em: https://recima21.com.br/index.php/recima21/article/view/42.

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01/05/2022

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Nascimento de Brito Silva, R., Castro dos Santos, N., & Feres, M. (2022). ÔMEGA-3 E ASPIRINA COMO ADJUVANTES NO TRATAMENTO PERIODONTAL: REVISÃO DE LITERATURA. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 3(5), e351295. https://doi.org/10.47820/recima21.v3i5.1295