ANEMIA HEMOLÍTICA INDUCIDA POR MEDICAMENTOS: UNA REVISIÓN SISTEMÁTICA

Autores/as

DOI:

https://doi.org/10.47820/recima21.v3i12.2463

Palabras clave:

Anemia hemolítica, Hemólisis, Medicamentos

Resumen

La anemia hemolítica inducida por fármacos (AHIM) es una complicación rara, resultante de la interacción de ciertas sustancias con la membrana del eritrocito, que puede ser fatal si no se aclara rápidamente. La anemia puede ocurrir en respuesta al uso de cualquier terapia farmacológica y muchas veces es infradiagnosticado. Así, el presente estudio tiene como objetivo realizar una revisión sistemática de la literatura sobre anemia hemolítica inducida por fármacos en PubMed, Biblioteca Virtual en Salud (BVS) y Capes Periodicals publicada en los últimos cinco años. Durante el estudio se seleccionaron 19 artículos científicos en la presente revisión, de los cuales 18 fueron reportes de casos y 1 fue un estudio retrospectivo. Se observó que en sólo un estudio, el desenlace clínico resultante de la AHIM fue la muerte del paciente. En total, la investigación reveló 19 principios activos relacionados con la hemólisis inducida por fármacos.

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Biografía del autor/a

Silvia Leticia do Nascimento e Silva Ferraz, Universidad Federal de Piauí

Estudiante de Farmacia en la UFPI.

Daniele Nataly de Alencar

Estudiante de Farmacia en la UFPI.

Yone Caroline Silva

Estudiante de Farmacia en la UFPI.

Janyerson Dannys Pereira da Silva

Doctorado en Farmacología por la Facultad Paulista de Medicina de la Universidad Federal de São Paulo

Éverton José Ferreira de Araújo

Farmacéutico. Doctorado en Biotecnología. Profesor de Hematología Clínica para Farmacia de la UFPI.

Citas

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Ishii H, Sato T, Ishibashi M, Yokoyama H, Saito T, Tasaki T, et al. A case of immune complex type hemolytic anemia by initial micafungin administration. Int J Infect Dis. 2022;0(0):755–757.

Wu Y, Wu Y, Ji Y, Liu Y, Wu D, Liang J, et al. Case Report: Oral Cimetidine Administration Causes Drug-Induced Immune Hemolytic Anemia by Eliciting the Production of Cimetidine-Dependent Antibodies and Drug-Independent Non-specific Antibodies. Front Med. 2021;8:1–9

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Publicado

24/12/2022

Cómo citar

Ferraz, S. L. do N. e S., de Alencar, D. N., Silva, Y. C., da Silva, J. D. P., & de Araújo, Éverton J. F. (2022). ANEMIA HEMOLÍTICA INDUCIDA POR MEDICAMENTOS: UNA REVISIÓN SISTEMÁTICA. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 3(12), e3122463. https://doi.org/10.47820/recima21.v3i12.2463