ANEMIA HEMOLÍTICA INDUZIDA POR MEDICAMENTOS: UMA REVISÃO SISTEMÁTICA

Autores

DOI:

https://doi.org/10.47820/recima21.v3i12.2463

Palavras-chave:

Anemia Hemolítica, Hemólise, Medicamentos

Resumo

A anemia hemolítica induzida por medicamentos (AHIM) é uma complicação rara, decorrente da interação de certas substâncias com a membrana dos eritrócitos, e que pode ser fatal se não elucidada rapidamente. A anemia pode ocorrer em resposta ao uso de qualquer terapia medicamentosa e muitas vezes é subdiagnosticada. Dessa maneira, o presente estudo tem como objetivo elaborar uma revisão sistemática da literatura sobre anemia hemolítica induzida por medicamentos nas bases de dados PubMed, Biblioteca Virtual em Saúde (BVS) e Periódicos Capes publicados nos últimos cinco anos. Ao longo do estudo foram selecionados 19 artigos científicos na presente revisão, dos quais 18 foram relatos de caso e 1 foi estudo retrospectivo. Observou-se que em apenas uma pesquisa o desfecho clínico decorrente da AHIM foi o óbito do paciente. Ao todo, a pesquisa revelou 19 princípios ativos relacionados com quadro de hemólise induzida por drogas.

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Biografias Autor

Silvia Leticia do Nascimento e Silva Ferraz, Universidade Federal do Piauí

Acadêmica de Farmácia da UFPI.

Daniele Nataly de Alencar

Acadêmica de Farmácia da UFPI.

Yone Caroline Silva

Acadêmica de Farmácia da UFPI.

Janyerson Dannys Pereira da Silva

Doutor em Farmacologia pela Escola Paulista de Medicina da Universidade Federal de São Paulo (EPM-Unifesp).

Éverton José Ferreira de Araújo

Farmacêutico-Bioquímico. Doutor em Biotecnologia. Professor de Hematologia Clínica para Farmácia da UFPI.

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Publicado

24/12/2022

Como Citar

Ferraz, S. L. do N. e S., de Alencar, D. N., Silva, Y. C., da Silva, J. D. P., & de Araújo, Éverton J. F. (2022). ANEMIA HEMOLÍTICA INDUZIDA POR MEDICAMENTOS: UMA REVISÃO SISTEMÁTICA. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 3(12), e3122463. https://doi.org/10.47820/recima21.v3i12.2463