GLIOBLASTOMA MULTIFORME: A BRIEF LITERATURE REVIEW
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https://doi.org/10.47820/recima21.v4i5.3118Palavras-chave:
Classification, Diagnosis, Etiology, Glioblastoma, TreatmentResumo
The objective of this article is to review the current state of knowledge about glioblastoma multiforme. Gliomas originated in astrocytes can be classified into four types: Pilocytic Astrocytoma, Fibrillary Astrocytoma, Anaplastic Astrocytoma and Glioblastoma Multiforme. Glioblastoma Multiforme is the most malignant and aggressive type of these. The risk factors for this tumor are still poorly understood, but it has been proven that ionizing radiation can be one of them. The diagnosis is made through the analysis of the critical manifestations and with complementary examinations such as computed tomography and magnetic resonance imaging. The treatments used against this type of tumor are maximum tumor resection, radiotherapy, chemotherapy, Tumor-Treating Fields, Bevacizumab, Oncolytic Viruses. Although there are several types of treatment, the prognosis of this tumor remains limited. More studies are needed tob investigate the effectiveness of the treatments used, as well as the access of the general public to these treatments in the public health system.
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DAVIS, Mary Elizabeth. Glioblastoma: Overview of Disease and Treatment. [S. l.], v. 20, n. 5, 2016.
FRANCIPANE, Maria Giovanna; DOURADINHA, Bruno; CHINNICI, Cinzia Maria; RUSSELLI, Giovanna; CONALDI, Pier Giulio; IANNOLO, Gioacchin. Zika virus: A new therapeutic candidate for glioblastoma treatment. International Journal of Molecular Sciences, [S. l.], v. 22, n. 20, 2021. DOI: 10.3390/ijms222010996.
GOVINDAN, Aparna; CHAKRABORTI, Shrijeet; MAHADEVAN, Anita; CHICKABASAVAIAH, Yasha T.; SANTOSH, Vani; SHANKAR, S. K. Histopathologic and immunohistochemical profile of spinal glioblastoma: a study of six cases. Brain tumor pathology, Japan, v. 28, n. 4, p. 297–303, 2011. DOI: 10.1007/s10014-011-0041-5.
GRITSCH, Simon; BATCHELOR, Tracy T.; GONZALEZ, Castro L. Nicolas. Diagnostic, therapeutic, and prognostic implications of the 2021 World Health Organization classification of tumors of the central nervous system. Cancer, United States, v. 128, n. 1, p. 47–58, 2022. DOI: 10.1002/cncr.33918.
HART, Michael G.; GARSIDE, Ruth; ROGERS, Gabriel; STEIN, Ken; GRANT, Robin. Temozolomide for high grade glioma. Cochrane Database of Systematic Reviews, [S. l.], v. 2013, n. 4, 2013. DOI: 10.1002/14651858.CD007415.pub2.
HEEMANN, Gabriel Carvalho; HEEMANN, Antônio Carlos Cunha. Glioblastoma multiforme recém-diagnosticado: diagnóstico e tratamento cirúrgico inicial. Acta méd. (Porto Alegre), [S. l.], p. 163–172, 2018.
JANJUA, Taskeen Iqbal et al. Frontiers in the treatment of glioblastoma: Past, present and emerging. Advanced Drug Delivery Reviews, [S. l.], v. 171, p. 108–138, 2021. DOI: https://doi.org/10.1016/j.addr.2021.01.012. Disponível em: https://www.sciencedirect.com/science/article/pii/S0169409X21000223.
PARPURA, Vladimir et al. Glial cells in (patho)physiology. Journal of Neurochemistry, [S. l.], v. 121, n. 1, p. 4–27, 2012. DOI: 10.1111/j.1471-4159.2012.07664.x.
RODRÍGUEZ-CAMACHO, Alejandro et al. Glioblastoma Treatment: State-of-the-Art and Future Perspectives. International Journal of Molecular Sciences, [S. l.], v. 23, n. 13, p. 1–35, 2022. DOI: 10.3390/ijms23137207.
SPLITTGERBER, Ryan. Snell Neuroanatomia Clínica. Brasil: Grupo GEN, 2021. E-book. ISBN 9788527737913.
VILELA, Manuel Augusto Pereira e HACKBART, Aline de Araújo. Oncologia básica: experiência multidisciplinar da UFPel. - Pelotas: Editora Universitária UFPel, 2008. 404 p. : il. 4
WIRSCHING, Hans Georg; GALANIS, Evanthia; WELLER, Michael. Glioblastoma. Handbook of Clinical Neurology, [S. l.], v. 134, p. 381–397, 2016. DOI: 10.1016/B978-0-12-802997-8.00023-2.
WU, Wei; KLOCKOW, Jessica L.; ZHANG, Michael; LAFORTUNE, Famyrah; CHANG, Edwin; JIN, Linchun; WU, Yang; DALDRUP-LINK, Heike E. Glioblastoma multiforme (GBM): An overview of current therapies and mechanisms of resistance. Pharmacological Research, [S. l.], v. 171, n. May, p. 105780, 2021. DOI: 10.1016/j.phrs.2021.105780. Disponível em: https://doi.org/10.1016/j.phrs.2021.105780.
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