BOTULINUM TOXIN TYPE A FOR TREATMENT OF MYOGENIC PAIN IN TEMPOROMANDIBULAR DISORDERS - AN INTEGRATIVE LITERATURE REVIEW

Authors

DOI:

https://doi.org/10.47820/recima21.v4i11.4394

Keywords:

Botulinum Toxin Type A, Pain, Temporomandibular Disorder, Treatment

Abstract

Botulinum toxin type A (BoNT/A) has been increasingly used in dentistry, either for aesthetic or therapeutic use, and a recent indication is for the treatment of myogenic pain in temporomandibular disorders (TMD). This integrative review of the literature aimed to compile scientific evidence on the effectiveness of this application of BoNT/A in myofascial pain symptomatology associated with TMD. After applying the inclusion and exclusion criteria, 13 scientific articles were selected to discuss the theme. The publications show the clear potential of BoNT/A to be among the therapeutic options for myogenic symptoms of TMD. However, this review revealed weaknesses in the understanding of pharmacokinetics and pharmacodynamics, in the choice of target anatomical sites, in doses and dosage, and in tissue adaptations to the presence of the drug. These are answers that future studies should aim at, but conditioned to the implementation of basic scientific precepts, such as the standardization of therapeutic protocols and investigative consensus.

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Author Biographies

Andressa Di Donato Martini Reis

Centro Universitário de Patos de Minas - UNIPAM.

Adriane de Fátima Vieira

Graduanda do curso de Odontologia pelo Centro Universitário de Patos de Minas.

Antônio Afonso Sommer

Doutor em Ortodontia e docente do Centro Universitário de Patos de Minas.

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Published

21/11/2023

How to Cite

Donato Martini Reis, A. D., de Fátima Vieira, A., & Afonso Sommer, A. (2023). BOTULINUM TOXIN TYPE A FOR TREATMENT OF MYOGENIC PAIN IN TEMPOROMANDIBULAR DISORDERS - AN INTEGRATIVE LITERATURE REVIEW. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 4(11), e4114394. https://doi.org/10.47820/recima21.v4i11.4394