USO DE PROBIÓTICOS NA PRÁTICA CLÍNICA DO TRANSTORNO DO ESPECTRO AUTISTA
DOI:
https://doi.org/10.47820/recima21.v3i6.1553Palavras-chave:
Probióticos, Transtorno do Espectro Autista, Microbiota GastrointestinalResumo
Objetivo: caracterizar os estudos relacionados ao uso de probióticos na prática clínica do transtorno do espectro autista. Métodos: trata-se de uma pesquisa exploratória e descritiva, sob forma de revisão integrativa, onde foram incluídos artigos originais realizados com indivíduos com diagnóstico de autismo que utilizavam probióticos, em um recorte temporal de dez anos (2009 a 2019). Resultados: as cepas probióticas utilizadas no autismo mais descritas nos estudos foram do gênero Lactobacillus (77,7%), Bifidobacterium (55,5%) e Streptococcus (33,3%). Foram relatadas melhoras em distúrbios comportamentais, cognitivos e gastrointestinais, assim como perda de sobrepeso e diminuição de marcadores inflamatórios. Os efeitos adversos de maior ocorrência foram diarreia (44,4%), constipação (22,2%), erupção cutânea (22,2%). Conclusão: Os estudos demonstraram associação benéfica com o uso de probióticos em crianças e jovens com autismo. A população dos estudos foi considerada pequena pelos autores, o que leva a proposta de ensaios clínicos controlados por placebo, com populações maiores, para obtenção de dados mais confiáveis.
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