THE USE OF STEM CELLS IN PERIODONTAL REGENERATION
DOI:
https://doi.org/10.47820/recima21.v5i12.6040Keywords:
Periodontitis, Regeneration, Stem CellsAbstract
Periodontitis is defined as a chronic infectious-inflammatory disease associated with a dysbiotic biofilm, leading to an imbalance in homeostasis, the loss of periodontal supporting tissues, and potentially culminating in tooth loss. The frequent occurrence of periodontal bone defects has driven growing interest in dentistry in periodontal regeneration, involving the constant search for new biomaterials and, more recently, the introduction of stem cell-based therapies. The aim of this literature review is to analyze the therapeutic potential of mesenchymal stem cells (MSCs) in periodontal regeneration, addressing the challenges associated with their clinical application. Mesenchymal stem cells, particularly derived from the periodontal ligament, have shown significant potential in regenerating damaged periodontal tissues. Studies indicate that these cells have the ability to differentiate into various cell types, including osteoblasts, cementoblasts, and fibroblasts, which are essential for the formation of new periodontal tissue.
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