EL USO DE CÉLULAS MADRE EN LA REGENERACIÓN PERIODONTAL
DOI:
https://doi.org/10.47820/recima21.v5i12.6040Palabras clave:
Periodontitis, Regeneración, Células MadreResumen
La periodontitis se define como una enfermedad crónica infecciosa e inflamatoria asociada a un biofilm disbiótico, que conduce a un desequilibrio en la homeostasis, la pérdida de los tejidos de soporte periodontal y, potencialmente, culmina en la pérdida de dientes. La frecuente aparición de defectos óseos periodontales ha generado un creciente interés en la odontología por la regeneración periodontal, lo que implica la búsqueda constante de nuevos biomateriales y, más recientemente, la introducción de terapias basadas en células madre. El objetivo de esta revisión de la literatura es analizar el potencial terapéutico de las células madre mesenquimales (CMM) en la regeneración periodontal, abordando los desafíos asociados con su aplicación clínica. Las células madre mesenquimales, en particular las derivadas del ligamento periodontal, han demostrado un potencial significativo para regenerar tejidos periodontales dañados. Los estudios indican que estas células tienen la capacidad de diferenciarse en varios tipos celulares, incluidos osteoblastos, cementoblastos y fibroblastos, esenciales para la formación de nuevo tejido periodontal.
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