PHARMACOTHERAPY APPLIED TO IMMUNOLOGICAL REACTIONS OF LEANSIS

Abstract

Leprosy Leprosy is a chronic infectious disease caused by Mycobacterium leprae, or Hansen's bacillus, which is a resistant gram-positive bacterium that can infect peripheral nerves. Thus, leprosy is considered a disease with a high infectious power and low pathogenic level, and therefore, associated with 95% immunity in most populations of occurrence In this context, the most effective model to be adopted for the control of leprosy it is based on the complementarity of actions; starting with early diagnosis, specialized and continuous treatment of diagnosed cases, prevention of disabilities, surveillance of the patient's home contacts, until discharge for cure. However, some patients may have a type 1 leprosy reaction, a reaction that often occurs soon after the start of treatment, with granulomatous inflammatory reactions and tissue necrosis concomitant with possible symptomatic neurological impairment. On the other hand, some patients may have a type 2 leprosy reaction, a reaction that usually occurs during and after treatment and is determined by the manifestation of sudden-appearing skin nodules. Thus, the treatment of leprosy is multidrug, outpatient and uses standardized therapeutic regimens, recommended by the World Health Organization. It is worth remembering that leprosy is a curable, controllable and treatment-free disease.