CLINICAL PROFILE AT ADMISSION OF PATIENTS WITH COVID-19 AND FACTORS ASSOCIATED WITH CLINICAL SEVERITY
DOI:
https://doi.org/10.47820/recima21.v5i4.5127Keywords:
COVID-19. Epidemiological Profile. Disease Severity.Abstract
The SARS-CoV-2 virus still maintains heterogeneity in relation to symptoms and clinical evolution. Thus, the objective of this study was to describe the characteristics of the admission of patients diagnosed with COVID-19 in a public hospital, associated with clinical severity. This is a cross-sectional study involving 170 patients hospitalized with COVID-19, from March 2020 to December 2021, allocated into two groups, according to the severity of the disease: moderate group (n=87) and severe group (n=83). The mean age observed in the population was 59.12 years, with a predominance of males (51.2%). The overall death rate of the patients studied was 42.4% (n=72), being 60.2% (n=50/83) vs. 25.3% (n=22/87) among critically ill patients vs. hospitalized for Severe Acute Respiratory Syndrome (SARS). Cardiovascular and infectious abnormalities were associated with patients classified as severe (p<0.05). In the multivariate analysis, patients with SARS were 407% more likely to have greater severity. For each unit of increase in indirect bilirubin and urea, at the time of admission, there was a 274% increase and a 2% increase in the chance of hospitalization in severe condition, respectively. Ultimately, it was found that patients with severe COVID-19 admitted to the ICU had considerable mortality and morbidity and a high incidence of SARS, which may have contributed to the outcome of death.
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