CLINICAL PROFILE AT ADMISSION OF PATIENTS WITH COVID-19 AND FACTORS ASSOCIATED WITH CLINICAL SEVERITY

Authors

DOI:

https://doi.org/10.47820/recima21.v5i4.5127

Keywords:

COVID-19. Epidemiological Profile. Disease Severity.

Abstract

The SARS-CoV-2 virus still maintains heterogeneity in relation to symptoms and clinical evolution. Thus, the objective of this study was to describe the characteristics of the admission of patients diagnosed with COVID-19 in a public hospital, associated with clinical severity. This is a cross-sectional study involving 170 patients hospitalized with COVID-19, from March 2020 to December 2021, allocated into two groups, according to the severity of the disease: moderate group (n=87) and severe group (n=83). The mean age observed in the population was 59.12 years, with a predominance of males (51.2%). The overall death rate of the patients studied was 42.4% (n=72), being 60.2% (n=50/83) vs. 25.3% (n=22/87) among critically ill patients vs. hospitalized for Severe Acute Respiratory Syndrome (SARS). Cardiovascular and infectious abnormalities were associated with patients classified as severe (p<0.05). In the multivariate analysis, patients with SARS were 407% more likely to have greater severity. For each unit of increase in indirect bilirubin and urea, at the time of admission, there was a 274% increase and a 2% increase in the chance of hospitalization in severe condition, respectively. Ultimately, it was found that patients with severe COVID-19 admitted to the ICU had considerable mortality and morbidity and a high incidence of SARS, which may have contributed to the outcome of death.

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Author Biographies

Claudionei Roessler

Universidade Estadual do Oeste do Paraná.

Renan William Mesquita

Universidade Estadual do Oeste do Paraná.

Karen Cristine Silva de Oliveira

Universidade Estadual do Oeste do Paraná.

Dalila Moter Benvegnú

Universidade Federal da Fronteira Sul.

Paulo Cezar Nunes Fortes

Universidade Estadual do Oeste do Paraná.

Leia Carolina Lúcio

Universidade Estadual do Oeste do Paraná.

Geraldo Emílio Vicentini

Universidade Estadual do Oeste do Paraná.

Lirane Elize Defante Ferreto

Universidade Estadual do Oeste do Paraná.

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Published

21/04/2024

How to Cite

Roessler, C., William Mesquita, R., Cristine Silva de Oliveira, K., Moter Benvegnú, D., Cezar Nunes Fortes, P., Carolina Lúcio, L., … Elize Defante Ferreto, L. (2024). CLINICAL PROFILE AT ADMISSION OF PATIENTS WITH COVID-19 AND FACTORS ASSOCIATED WITH CLINICAL SEVERITY. RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 5(4), e545127. https://doi.org/10.47820/recima21.v5i4.5127