THE ROLE OF PHYSICAL ACTIVITY IN PREVENTING THE PROGRESSION OF ALZHEIMER'S DISEASE: A LITERATURE REVIEW
DOI:
https://doi.org/10.47820/recima21.v5i5.5197Keywords:
Physical activity. Exercise. Prevention. Alzheimer's disease. Brain health.Abstract
Introduction: Alzheimer's disease (AD) is a common form of dementia and represents a growing public health challenge due to the aging of the population. Physical activity has been studied as a potential intervention in the prevention and treatment of AD. Objective: This literature review seeks to demonstrate the role of physical activity in preventing the progression of AD. Methods: This literature review was conducted through a systematic search of scientific literature published in the last 20 years, covering the period from 2004 to 2024, using specific inclusion and exclusion criteria, and electronic databases: PubMed, Web of Science, Scopus and Google Scholar. Results and Discussion: Consistent evidence has shown an inverse association between physical activity and the risk of developing AD, with additional benefits in cognitive function in patients diagnosed with the disease. Neurobiological mechanisms, such as reducing inflammation and promoting neuroplasticity, may contribute to these beneficial effects. However, adherence to exercise programs remains a challenge, especially in vulnerable populations. Conclusion: Physical activity is emerging as a promising intervention in the prevention and treatment of AD, with the potential to improve brain health and quality of life. Integrated and personalized strategies are needed to maximize the benefits of physical activity in vulnerable populations, highlighting the importance of physical activity in the treatment of AD.
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