INVESTIGACIÓN CON PACIENTES CON ENFERMEDAD DE PARKINSON EN BRASIL – UNA REVISIÓN INTEGRADORA
DOI:
https://doi.org/10.47820/recima21.v4i6.3285Palabras clave:
enfermedad crónica que afectaResumen
La enfermedad de Parkinson (EP) es una enfermedad crónica que afecta a unos 6,1 millones de personas y que ocupa el primer lugar en el ranking de las afecciones neurodegenerativas que más crecen en número de portadores en el mundo (DORSEY et al, 2018). La EP, que es conocida principalmente por sus síntomas motores, hoy tiene un cuadro clínico ampliado, con síntomas neuropsiquiátricos, autonómicos y sensoriales. Hasta la fecha, el tratamiento de la EP se realiza principalmente con levodopa (L-DOPA), que, al principio, es eficaz para los síntomas motores. Sin embargo, la terapia no interrumpe la progresión de la enfermedad y con el tiempo puede perder su eficacia, requiriendo ajustes y complementaciones con otros fármacos y terapias. Por lo tanto, el objetivo de este estudio es compilar las terapias para la enfermedad de Parkinson que actualmente están siendo investigadas por ensayos clínicos en el contexto brasileño. Para ello, se realizó una revisión integradora de la literatura científica basada en artículos disponibles en las siguientes plataformas: Scientific Electronic Library Online – SCIELO, la U.S. National Library of Medicine (NLM) – PubMed y ScienceDirect. Su objetivo, a través de esto, es recopilar información útil para el tratamiento clínico más amplio / holístico de pacientes con enfermedad de Parkinson. Los estudios han demostrado el valor de la estimulación cerebral profunda (DBS), L-DOPA más allá de los síntomas motores, el ejercicio y el manejo de caídas en el tratamiento de la enfermedad.
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