MECANISMOS FISIOPATOLÓGICOS E CONDUTAS TERAPÊUTICAS NA SÍNDROME DO OVÁRIO POLICÍSTICO: UMA REVISÃO BIBLIOGRÁFICA
DOI:
https://doi.org/10.47820/recima21.v5i4.5094Palavras-chave:
Síndrome do Ovário Policístico. Fisiopatologia. Terapêutica.Resumo
Introdução: A Síndrome do Ovário Policístico (SOP) é uma condição endócrina complexa que afeta mulheres em idade reprodutiva, apresentando uma ampla gama de manifestações clínicas e metabólicas. Objetivo: analisar os mecanismos fisiopatológicos e condutas terapêuticas da SOP, fornecendo uma síntese atualizada da literatura científica. Metodologia: Trata-se de uma revisão bibliográfica, utilizando artigos presentes nas seguintes bases de dados: PubMed, Scopus e SciELO Foram incluídos artigos originais e revisões sistemáticas em inglês e português publicadas entre 2013 e 2024, que abordassem sobre mecanismos fisiopatológicos e condutas terapêuticas da SOP. Após a análise, foram selecionados 37 artigos para a confecção dessa revisão bibliográfica. Resultados e Discussão: A SOP é uma doença heterogênea caracterizada por hiperandrogenismo, ovulação disfuncional e morfologia dos ovários policísticos, acompanhada de anormalidades metabólicas, como resistência à insulina e obesidade. As abordagens terapêuticas para a SOP variam desde intervenções farmacológicas até modificações no estilo de vida. Os tratamentos farmacológicos visam normalizar os níveis hormonais, restaurar a ovulação e melhorar os sintomas clínicos, incluindo contraceptivos orais combinados, antiandrogênios e sensibilizadores de insulina, como a metformina.. Conclusão: A SOP continua sendo uma condição desafiadora para pacientes e profissionais de saúde, dada a sua complexidade fisiopatológica e as diversas manifestações clínicas.
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