AVALIAÇÃO DA EFICÁCIA DAS NOVAS TERAPIAS ANTICOAGULANTES ORAIS NA PREVENÇÃO DE EVENTOS RELACIONADOS À FIBRILAÇÃO ATRIAL: UMA REVISÃO BIBLIOGRÁFICA
DOI:
https://doi.org/10.47820/recima21.v5i5.5203Palavras-chave:
Fibrilação Atrial, Novas Terapias Anticoagulantes Orais, Prevenção de Eventos CardiovascularesResumo
A fibrilação atrial é uma condição clínica comum associada a um aumento significativo no risco de eventos cardiovasculares, como o acidente vascular cerebral (AVC). O advento das novas terapias anticoagulantes orais, como os inibidores diretos do fator Xa e da trombina, trouxe novas perspectivas para o tratamento e prevenção desses eventos. Objetivo: Esta revisão bibliográfica tem como objetivo avaliar a eficácia das novas terapias anticoagulantes orais na prevenção de eventos cardiovasculares relacionados à fibrilação atrial. Métodos: Esta revisão bibliográfica foi conduzida por meio de uma busca sistemática na literatura científica publicada nos últimos 15 anos, abrangendo o período de 2009 a 2024, utilizando as bases de dados PubMed, Web of Science, Scopus e Google Scholar. Foram incluídos estudos originais e revisões que investigaram as características das novas terapias anticoagulantes orais e sua eficácia na prevenção de eventos cardiovasculares em pacientes com fibrilação atrial. Resultados e Discussão: Os estudos revisados destacaram a eficácia das novas terapias anticoagulantes orais na redução do risco de eventos cardiovasculares, como o AVC, em comparação com a varfarina. Além disso, esses medicamentos mostraram um perfil de segurança favorável, com menor incidência de sangramento intracraniano. A adesão e conformidade ao tratamento também foram ressaltadas como vantagens das novas terapias, contribuindo para uma melhor qualidade de vida dos pacientes. Conclusão: A revisão evidenciou a importância das novas terapias anticoagulantes orais na prática clínica, fornecendo uma análise abrangente e atualizada sobre sua eficácia, segurança e impacto econômico.
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