EVALUATING THE EFFICACY OF NEW ORAL ANTICOAGULANT THERAPIES IN PREVENTING EVENTS RELATED TO ATRIAL FIBRILLATION: A LITERATURE REVIEW
DOI:
https://doi.org/10.47820/recima21.v5i5.5203Keywords:
Atrial Fibrillation, Novel Oral Anticoagulant Therapies, Prevention of Cardiovascular Events.Abstract
Introduction: Atrial fibrillation is a common clinical condition associated with a significant increase in the risk of cardiovascular events, such as stroke. The advent of new oral anticoagulant therapies, such as direct inhibitors of factor Xa and thrombin, has brought new perspectives for the treatment and prevention of these events. Objective: This literature review aims to evaluate the efficacy of new oral anticoagulant therapies in the prevention of cardiovascular events related to atrial fibrillation. Methods: This literature review was conducted through a systematic search of the scientific literature published in the last 15 years, covering the period from 2009 to 2024, using the PubMed, Web of Science, Scopus, and Google Scholar databases. Original studies and reviews investigating the characteristics of new oral anticoagulant therapies and their efficacy in preventing cardiovascular events in patients with atrial fibrillation were included. Results and Discussion: The reviewed studies highlighted the efficacy of new oral anticoagulant therapies in reducing the risk of cardiovascular events, such as stroke, compared to warfarin. In addition, these drugs have shown a favorable safety profile, with a lower incidence of intracranial bleeding. Adherence and compliance with treatment were also highlighted as advantages of the new therapies, contributing to a better quality of life for patients. Conclusion: The review highlighted the importance of new oral anticoagulant therapies in clinical practice, providing a comprehensive and up-to-date analysis of their efficacy, safety, and economic impact.
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