MAGNETIC SCAFFOLDS MADE OF CHITOSAN AND/OR HYDROXYAPATITE FOR BONE TISSUE REGENERATION: A REVIEW OF THE LITERATURE
DOI:
https://doi.org/10.47820/recima21.v4i3.2936Keywords:
Magnetic scaffolds. Chitosan. Hydroxyapatite. Bone Regeneration.Abstract
The incorporation and exploration of particles with magnetic properties as an enhancer of bone regeneration processes through three-dimensional scaffolds has been a strategy in bone tissue engineering, which allows obtaining structures with responsive capacity to external stimuli, intelligent and bioactive. In this sense, this paper proposes a systematic review based on primary research articles focusing on magnetic chitosan and/or hydroxyapatite scaffolds in bone tissue regeneration. To this end, a search was performed on the platforms Science Direct, Pubmed and Web of Science in the period between 2020 and 2022 and the review was conducted using the Start software. Inclusion criteria were used to select the most relevant journals and it was observed that among the magnetic chitosan and/or hydroxyapatite scaffold strategies reported, the most significant involved induction of endochondral osteogenesis, increase in blood vessel formation pathways in injured bone tissue, drug delivery system, delivery of growth factors, and tumor cell combat. The results showed that these systems have promising potential for application in bone regeneration.
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