CIENCIA Y ENDODONCIA PARA LA ODONTOLOGÍA ODONTOPEDIATRÍA: UNA REVISIÓN NARRATIVA
DOI:
https://doi.org/10.47820/recima21.v5i8.5563Palabras clave:
Endodontia, odontopediatria, LSTR.Resumen
El campo de la endodoncia está en constante evolución y la investigación se centra en el desarrollo de técnicas y materiales innovadores para proteger los tejidos periapicales. La técnica LSTR (Estilización y Reparación de Lesiones y Tejidos) se ha mostrado prometedora para eliminar lesiones y reparar tejidos dentales, pero su eficacia y seguridad aún no están claras. Este estudio tiene como objetivo evaluar la efectividad del LSTR en el seguimiento a largo plazo en el tratamiento de lesiones pulpares parciales o totales en dientes primarios, comparándolo con otras técnicas de endodoncia. La metodología fue una búsqueda electrónica en las bases de datos de PubMed, LILACS y Scopus de publicaciones en inglés desde el 2010 inicio hasta el 15 de julio de 2024, de los cuales se seleccionaron 20 artículos referentes al tema. Resultados nos dieron a entender cómo se inicia un proceso inflamatorio y de reparación en la pulpa dental, los antibióticos no participan de estas etapas y otras sustancias tradicionales nos citotóxicas, los materiales biológicos si forman parte de la formación y activación de mediadores de regeneración y revascularización al tener actividad con las células madre y formación de andamios. Conclusión: Se han mencionado también las células madre SHED, DPSC, SCAP y PDLSC como prometedoras en medicina regenerativa y terapias de ingeniería de tejidos. También se describe que uso de biomateriales debe ser la nueva terapia para seguir basada en la evidencia científica para el tratamiento de terapias pulpares en odontopediatría que busquen regeneración pulpar o revascularización.
Descargas
Referencias
AGARWAL, S. R.; BENDGUDE, V. D.; KAKODKAR, P. Evaluation of Success Rate of Lesion Sterilization and Tissue Repair Compared to Vitapex in Pulpally Involved Primary Teeth: A Systematic Review. Journal of Conservative Dentistry: JCD, v. 22, n. 6, p. 510, 2019. https://doi.org/10.4103/JCD.JCD_76_20 DOI: https://doi.org/10.4103/JCD.JCD_76_20
BADAWY, S.; YANG, Y. Q.; LIU, Y.; MARAWAN, M. A.; ARES, I.; MARTINEZ, M. A.; MARTÍNEZ-LARRAÑAGA, M. R.; WANG, X.; ANADÓN, A.; MARTÍNEZ, M. Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism. Critical Reviews in Toxicology, v. 51, n. 9, p. 754–787, 2021. https://doi.org/10.1080/10408444.2021.2024496 DOI: https://doi.org/10.1080/10408444.2021.2024496
CASTRO, M.; LIMA, M.; LIMA, C.; MOURA, M.; MOURA, J.; MOURA, L. Lesion sterilization and tissue repair with chloramphenicol, tetracyline, zinc oxide/eugenol paste versus conventional pulpectomy: A 36-month randomized controlled trial. International Journal of Paediatric Dentistry, v. 33, n. 4, p. 335–345, 2023. https://doi.org/10.1111/IPD.13056 DOI: https://doi.org/10.1111/ipd.13056
CINTRA, L. T. A.; GOMES, M. S.; DA SILVA, C. C.; FARIA, F. D.; BENETTI, F.; COSME-SILVA, L.; SAMUEL, R. O.; PINHEIRO, T. N.; ESTRELA, C.; GONZÁLEZ, A. C.; SEGURA-EGEA, J. J. Evolution of endodontic medicine: a critical narrative review of the interrelationship between endodontics and systemic pathological conditions. Odontology, v. 109, n. 4, p. 741–769, 2021. https://doi.org/10.1007/S10266-021-00636-X DOI: https://doi.org/10.1007/s10266-021-00636-x
DONG, X.; XU, X. Bioceramics in Endodontics: Updates and Future Perspectives. Bioengineering (Basel, Switzerland), v. 10, n. 3, 2023. https://doi.org/10.3390/BIOENGINEERING10030354 DOI: https://doi.org/10.3390/bioengineering10030354
DUARTE, M. L.; PIRES, P. M.; FERREIRA, D. M.; PINTOR, A. V. B.; DE ALMEIDA NEVES, A.; MAIA, L. C.; PRIMO, L. G. Is there evidence for the use of lesion sterilization and tissue repair therapy in the endodontic treatment of primary teeth? A systematic review and meta-analyses. Clinical Oral Investigations, v. 24, n. 9, p. 2959–2972, 2020. https://doi.org/10.1007/S00784-020-03415-0 DOI: https://doi.org/10.1007/s00784-020-03415-0
FIGUEROA-BANDA, R. A.; FIGUEROA-CASTELLANOS, K. F.; CHÁVEZ-OBLITAS, E. A.; GUILLEN-NUÑEZ, M. E.; AYQUI-CUEVA, F.; DEL-CARPIO-M, B. A.; BELLIDO-VALLEJO, K. L.; GÓMEZ, B. Theoretical Study at the Molecular Mechanics Level of the Interaction of Tetracycline and Chloramphenicol with the Antibiotic Receptors Present in Enterococcus faecalis (Q839F7) and Streptococcus mutans (Q8DS20). Antibiotics (Basel, Switzerland), v. 11, n. 11, 2022. https://doi.org/10.3390/ANTIBIOTICS11111640 DOI: https://doi.org/10.3390/antibiotics11111640
GARROCHO-RANGEL, A.; JALOMO-ÁVILA, C.; ROSALES-BERBER, M. Á.; POZOS-GUILLÉN, A. Lesion Sterilization Tissue Repair (LSTR) Approach of Non-Vital Primary Molars with A Chloramphenicol-Tetracycline-ZOE Antibiotic Paste: A Scoping Review. The Journal of Clinical Pediatric Dentistry, v. 45, n. 6, p. 369–375, 2021. https://doi.org/10.17796/1053-4625-45.6.1 DOI: https://doi.org/10.17796/1053-4625-45.6.1
GOMES, B. P. F. A.; AVEIRO, E.; KISHEN, A. Irrigants and irrigation activation systems in Endodontics. Brazilian Dental Journal, v. 34, n. 4, p. 1–33, 2023. https://doi.org/10.1590/0103-6440202305577 DOI: https://doi.org/10.1590/0103-6440202305577
JESKE, A. H. Contemporary dental pharmacology. [S. l.: s. n.], 2024. Vol. 2. https://books.google.com/books/about/Contemporary_Dental_Pharmacology.html?hl=es&id=IdFx0AEACAAJ
MANES URIBE, C.; RESTREPO, M.; DIEGO MEJÍA, J. Técnica LSTR con pasta CTZ para el tratamiento de la necrosis pulpar en molares primarios. Reporte de caso. Revista de Odontopediatría Latinoamericana, v. 13, 2023. https://doi.org/10.47990/ALOP.V13I.568 DOI: https://doi.org/10.47990/alop.v13i.568
MIURA, C. A. S.; SÁ, M. S.; LIMA, R. S.; MACHADO, M. A. A. M.; TELLES, P. D. S. Avaliação da toxicidade de materiais endodônticos em células-tronco da polpa dentária. ROBRAC, 2010. http://files.bvs.br/upload/S/0104-7914/2010/v19n50/a1547.pdf
RETAMOZO, B.; SHABAHANG, S.; JOHNSON, N.; APRECIO, R. M.; TORABINEJAD, M. Minimum contact time and concentration of sodium hypochlorite required to eliminate Enterococcus faecalis. Journal of Endodontics, v. 36, n. 3, p. 520–523, 2010. https://doi.org/10.1016/J.JOEN.2009.12.005 DOI: https://doi.org/10.1016/j.joen.2009.12.005
ROMERO-MIGUEL, D.; LAMANNA-RAMA, N.; CASQUERO-VEIGA, M.; GÓMEZ-RANGEL, V., DESCO, M.; SOTO-MONTENEGRO, M. L. Minocycline in neurodegenerative and psychiatric diseases: An update. European Journal of Neurology, v. 28, n. 3, p. 1056–1081, 2021. https://doi.org/10.1111/ENE.14642 DOI: https://doi.org/10.1111/ene.14642
SAIN, S. J. R. S. A.; GEORGE, S.; ISSAC, J. S.; JOHN, S. A. Lesion Sterilization and Tissue Repair-Current Concepts and Practices. International Journal of Clinical Pediatric Dentistry, v. 11, n. 5, p. 446–450, 2018. https://doi.org/10.5005/JP-JOURNALS-10005-1555 DOI: https://doi.org/10.5005/jp-journals-10005-1555
SCHAFFER, S. D.; HUTCHISON, C. A.; ROUCHON, C. N.; MDLULI, N. V.; WEINSTEIN, A. J.; MCDANIEL, D.; FRANK, K. L. Diverse Enterococcus faecalis strains show heterogeneity in biofilm properties. Research in Microbiology, v. 174, n. 1–2, p. 103986, 2023. https://doi.org/10.1016/J.RESMIC.2022.103986 DOI: https://doi.org/10.1016/j.resmic.2022.103986
SEQUEIRA, D. B.; DIOGO, P.; GOMES, B. P. F. A.; PEÇA, J.; SANTOS, J. M. M. Scaffolds for Dentin-Pulp Complex Regeneration. Medicina (Kaunas, Lithuania), v. 60, n. 1, 2023. https://doi.org/10.3390/MEDICINA60010007 DOI: https://doi.org/10.3390/medicina60010007
SHANKAR, K.; RAMKUMAR, H.; DHAKSHINAMOORTHY, S.; PAULINDRARAJ, S.; JAYAKARAN, T. G.; BOMMAREDDY, C. S. Comparison of Modified Triple Antibiotic Paste in Two Concentrations for Lesion Sterilization and Tissue Repair in Primary Molars: An In Vivo Interventional Randomized Clinical Trial. International Journal of Clinical Pediatric Dentistry, v. 14, n. 3, p. 388–392, 2021. https://doi.org/10.5005/JP-JOURNALS-10005-1951 DOI: https://doi.org/10.5005/jp-journals-10005-1951
SHARIATI, A.; ARSHADI, M.; KHOSROJERDI, M. A.; ABEDINZADEH, M.; GANJALISHAHI, M.; MALEKI, A.; HEIDARY, M.; KHOSHNOOD, S. The resistance mechanisms of bacteria against ciprofloxacin and new approaches for enhancing the efficacy of this antibiotic. Frontiers in Public Health, v. 10, 2022. https://doi.org/10.3389/FPUBH.2022.1025633 DOI: https://doi.org/10.3389/fpubh.2022.1025633
SHI, X.; MAO, J.; LIU, Y. Pulp stem cells derived from human permanent and deciduous teeth: Biological characteristics and therapeutic applications. Stem Cells Translational Medicine, v. 9, n. 4, p. 445–464, 2020. https://doi.org/10.1002/SCTM.19-0398 DOI: https://doi.org/10.1002/sctm.19-0398
SINGH, K.; REDDY, A.; ARYA, A.; SRIDHAR, V.; RANJAN, M.; BULBULE, N. Lesion Sterilization Tissue Repair: A Review. Journal of Pharmacy & Bioallied Sciences, v. 16, n. Suppl 1, p. S75–S77, 2024. https://doi.org/10.4103/JPBS.JPBS_411_23 DOI: https://doi.org/10.4103/jpbs.jpbs_411_23
SINGH, S.; KHANNA, D.; KALRA, S. Minocycline and Doxycycline: More Than Antibiotics. Current Molecular Pharmacology, v. 14, n. 6, p. 1046–1065, 2021. https://doi.org/10.2174/1874467214666210210122628 DOI: https://doi.org/10.2174/1874467214666210210122628
SMILACK, J. D. Tetraciclinas, sulfamidas y metronidazol. Mayo Clinic Proceedings, v. 74, n. 7, p. 727–729, 1999. https://doi.org/10.4065/74.7.727 DOI: https://doi.org/10.4065/74.7.727
SONG, W.; LI, S.; TANG, Q.; CHEN, L.; YUAN, Z. In vitro biocompatibility and bioactivity of calcium silicate based bioceramics in endodontics (Review). International Journal of Molecular Medicine, v. 48, n. 1, 2021. https://doi.org/10.3892/IJMM.2021.4961 DOI: https://doi.org/10.3892/ijmm.2021.4961
UREÑA, J. L. Microbiología oral. Libro, v. 3, p. 49–58, apr. 2002. https://books.google.com/books/about/Microbiologia_oral_2_Ed.html?hl=es&id=yYaGAAAACAAJ
XIE, Z.; SHEN, Z.; ZHAN, P.; YANG, J.; HUANG, Q.; HUANG, S.; CHEN, L.; LIN, Z. Functional Dental Pulp Regeneration: Basic Research and Clinical Translation. International Journal of Molecular Sciences, v. 22, n. 16, 2021. https://doi.org/10.3390/IJMS22168991 DOI: https://doi.org/10.3390/ijms22168991
ZAKY, S. H.; SHEHABELDIN, M.; RAY, H.; SFEIR, C. The role of inflammation modulation in dental pulp regeneration. European Cells & Materials, v. 41, p. 184–193, 2021. https://doi.org/10.22203/ECM.V041A13 DOI: https://doi.org/10.22203/eCM.v041a13
ZOU, J.; MAO, J.; SHI, X. Influencing factors of pulp-dentin complex regeneration and related biological strategies. Zhejiang Da Xue Xue Bao. Yi Xue Ban = Journal of Zhejiang University. Medical Sciences, v. 51, n. 3, p. 350–361, 2022. https://doi.org/10.3724/ZDXBYXB-2022-0046 DOI: https://doi.org/10.3724/zdxbyxb-2022-0046
Descargas
Publicado
Número
Sección
Categorías
Licencia
Derechos de autor 2024 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
Esta obra está bajo una licencia internacional Creative Commons Atribución 4.0.
Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.
