NETWORKING BETWEEN COVID-19 AND AUTOIMMUNE DISEASES: LITERATURE REVIEW

Authors

DOI:

https://doi.org/10.47820/recima21.v3i10.2086

Keywords:

Autoantibodies., COVID-19, Autoimmune disease.

Abstract

Introduction: COVID-19 is an infectious disease caused by coronavirus-2 associated with severe acute respiratory syndrome (SARS-CoV-2). Although most infected individuals are asymptomatic, a proportion of patients with COVID-19 develop severe disease with multiple organ damage. Aim: The present study aimed to correlate autoimmune diseases with the mechanisms triggered by SARS-CoV-2 infection. Methodology: The Center for Biotechnology Information (PubMed) and the Scientific Electronic Library Online (SciELO) databases were used for this study. As inclusion criteria, articles arising from the correlation of autoimmune diseases with COVID-19 were selected. Development: Studies have elucidated that SARS-CoV-2 can disrupt self-tolerance and trigger immune responses through cross-reactivity with host cells, culminating in the production of autoantibodies, and consequently, the development of autoimmune diseases. However, the risk of infection and prognosis of COVID-19 in patients with autoimmune diseases remains controversial, and further studies are needed to understand the complexity of the correlation between the virus and the onset of these diseases. Conclusion: Understanding the immunological mechanisms involved is of fundamental importance, and may open new avenues for the design of effective therapies.

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Author Biographies

  • Anne Kareninne Domingos Matos

    Medical student at the Barão de Mauá University Center.

  • Bruno Vinicius Aquino Mendes

    Academic of the Medicine course at the Barão de Mauá University Center.

  • Mateus Franzini

    Academic of the Medicine course at the Barão de Mauá University Center.

  • Matheus Guedes Stehling

    Academic of the Medicine course at the Barão de Mauá University Center.

  • Rodolfo Oliveira Alves

    Academic of the Medicine course at the Barão de Mauá University Center.

  • Cristiane Tefé-Silva

    Professor at the Barão de Mauá University Center.

  • Karina Furlani Zoccal

    Docente e coordenadora da Liga Acadêmica de Patologia e Imunologia, Centro Universitário Barão de Mauá (CBM), Ribeirão Preto, São Paulo, Brasil. 

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Published

27/10/2022

How to Cite

NETWORKING BETWEEN COVID-19 AND AUTOIMMUNE DISEASES: LITERATURE REVIEW. (2022). RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218, 3(10), e3102086. https://doi.org/10.47820/recima21.v3i10.2086