NETWORKING ENTRE A COVID-19 E DOENÇAS AUTOIMUNES: REVISÃO DE LITERATURA

Autores

DOI:

https://doi.org/10.47820/recima21.v3i10.2086

Palavras-chave:

Autoanticorpos, COVID-19, Doença autoimune

Resumo

Introdução: A COVID-19 é uma doença infecciosa causada pelo coronavírus-2 associado à síndrome respiratória aguda grave (SARS-CoV-2). Embora a maioria dos indivíduos infectados sejam assintomáticos, uma proporção de pacientes com COVID-19 desenvolve doença grave com lesões em múltiplos órgãos. Objetivo: O presente estudo teve como objetivo correlacionar as doenças autoimunes com os mecanismos desencadeados pela infecção do SARS-CoV-2. Metodologia: Para este estudo, as bases de dados Center for Biotechnology Information (PubMed) e a biblioteca eletrônica Scientific Eletronic Library Online (SciELO), foram utilizadas. Como critério de inclusão foram selecionados artigos decorrentes da correlação das doenças autoimunes com a COVID-19. Desenvolvimento: Estudos elucidaram que o SARS-CoV-2 pode perturbar a autotolerância e desencadear respostas imunes por meio da reatividade cruzada com as células hospedeiras, culminando na produção de autoanticorpos, e consequentemente, no desenvolvimento de doenças autoimunes. No entanto, o risco de infecção e o prognóstico da COVID-19 em pacientes com doenças autoimunes permanece controverso, sendo necessários mais estudos para compreender a complexidade da correlação entre o vírus e o desencadeamento dessas doenças. Conclusão: É de fundamental importância a compreensão dos mecanismos imunológicos envolvidos, podendo abrir novos caminhos para a concepção de terapias eficazes.

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Biografias Autor

Acadêmica do curso de Medicina do Centro Universitário Barão de Mauá.

Bruno Vinicius Aquino Mendes

Acadêmico do curso de Medicina do Centro Universitário Barão de Mauá.

Mateus Franzini

Acadêmico do curso de Medicina do Centro Universitário Barão de Mauá.

Matheus Guedes Stehling

Acadêmico do curso de Medicina do Centro Universitário Barão de Mauá.

Rodolfo Oliveira Alves

Acadêmico do curso de Medicina do Centro Universitário Barão de Mauá.

Cristiane Tefé-Silva

Docente do Centro Universitário Barão de Mauá.

Karina Furlani Zoccal

Docente e coordenadora da Liga Acadêmica de Patologia e Imunologia, Centro Universitário Barão de Mauá (CBM), Ribeirão Preto, São Paulo, Brasil. 

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Publicado

27/10/2022

Como Citar

, Mendes, B. V. A. ., Franzini, M., Stehling, M. G., Alves, R. O., Tefé-Silva, C., & Zoccal, K. F. . (2022). NETWORKING ENTRE A COVID-19 E DOENÇAS AUTOIMUNES: REVISÃO DE LITERATURA. RECIMA21 -Revista Científica Multidisciplinar - ISSN 2675-6218, 3(10), e3102086. https://doi.org/10.47820/recima21.v3i10.2086