THE CORRELATION BETWEEN NUTRIENTS AND EVOLUTION AND PROGNOSIS OF ALZHEIMER'S DISEASE
DOI:
https://doi.org/10.47820/recima21.v3i7.1705Keywords:
food, alzheimer's dementia, cognitive declineAbstract
Alzheimer's is the most age-related neurodegenerative disease, and several cognitive and neuropsychiatric manifestations are described that have progressive deficiency and disability. From the clinical evolution of the cases, other alterations associated with memory and cognition were evidenced, being cited as a factor of delay in the evolution of the disease the feeding pattern of the senior. This study aims to demonstrate the relationship between nutrition and progression of Alzheimer's disease, both as a form of prevention and improvements in the clinical conditions of patients. Methodology: Original articles were analyzed, whose research was carried out on the electronic platforms United States National Library of Medicine (PubMed) and Google Scholar (Academic Google). Conclusion: With the evolution of this study, it was possible to review, in the medical literature, the main aspects that reveal the development/delay of Alzheimer's disease and its relationship with the feeding of the elderly. Thus, studies have shown that nutrition is directly related to the prognosis of the disease.
Downloads
References
BALBINO, C.S. A influência da alimentação no tratamento da doença de Alzheimer, Brazilian Journal of Health Review. 2021. Disponível em: https://www.brazilianjournals.com/index.php/BJHR/article/viewFile/29583/23326
CÂMARA, A.B. Receptores neurais e a doença de Alzheimer: uma revisão sistemática da literatura sobre as famílias de receptores mais associadas a doença, suas funções e áreas de expressão. Jornal Brasileiro de Psiquiatria. 68 (3), 2019. Disponível em: https://doi.org/10.1590/0047-2085000000242.
CAVIGLIONI, V.M.; SILVA, L.B. O papel dos padrões alimentares na prevenção de demência: revisão da literatura. Journal of the Health Sciences Institute. 2021;39(4):279-85. Disponível em: https://repositorio.unip.br/wp-content/uploads/tainacan-items/50324/83973/10V39_n4_2021_p279a285.pdf.
CROUS-BOU, M., MINGUILLÓN, C., GRAMUNT, N. et al. Alzheimer’s disease prevention: from risk factors to early intervention. Alzheimer Research e Therapy 9, 71. 2017. Disponível em: https://alzres.biomedcentral.com/articles/10.1186/s13195-017-0297-z
KWOK , T. et al. A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients. Clinical Nutrition. 2020 Aug; 39(8):2399-2405. Disponível em: https://www.clinicalnutritionjournal.com/article/S0261-5614(19)33132-2/fulltext.
LIU, X. et al. Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline. Contemporary Clinical Trials. 2021. Disponível em: https://www.sciencedirect.com/science/article/pii/S1551714421000069?via%3Dihub
MATTON, A. S. et al. 27-Hydroxycholesterol, cognition, and brain imaging markers in the FINGER randomized controlled trial. Alzheimer Research Therapy 13, 56. 2021. Disponível em: https://alzres.biomedcentral.com/articles/10.1186/s13195-021-00790-y.
MOHAMED, W.A. et al. A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway. Biomedicine e Pharmacotherapy. 2019. Mar; 111:714-723. Disponível em: https://www.sciencedirect.com/science/article/pii/S075333221836935X?via%3Dihub.
MORRILL, S.J.; GIBAS, K.J. Ketogenic diet rescues cognition in ApoE4+ patient with mild Alzheimer's disease: A case study. Diabetes Metabolic Syndrome: Clinical Research e Reviews. 2019;13(2):1187-1191. Disponível em: https://www.sciencedirect.com/science/article/abs/pii/S1871402118306684
NAN HU. et al. Nutrition and the Risk of Alzheimers Disease. Hindawi Publishing Corporation. 10 June 2013. Disponível em: https://www.hindawi.com/journals/bmri/2013/524820/.
NOLAN, J.M. et al. Nutritional Intervention to Prevent Alzheimer’s Disease: Potential Benefits of Xanthophyll Carotenoids and Omega-3 Fatty Acids Combined. Journal of Alzheimers Disease. 2018; 64(2):367-378. Disponível em: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad180160.
OTA, M. et al. Effects of a medium-chain triglyceride-based ketogenic formula on cognitive function in patients with mild-to-moderate Alzheimer's disease. Neuroscience Letters. 2019. Jan 18; 690:232-236. Disponível em: https://www.sciencedirect.com/science/article/pii/S0304394018307304?via%3Dihub
PERŁA-KAJÁN, J. et al. Paraoxonase 1, B Vitamins Supplementation, and Mild Cognitive Impairment. Journal of Alzheimers Disease. 2021. 81(3):1211-1229. Disponível em: https://content.iospress.com/articles/journal-of-alzheimers-disease/jad210137
PHILLIPS, M.C.L.; DEPREZ, L.M.; MORTIMER, G.M.N. et al. Randomized crossover trial of a modified ketogenic diet in Alzheimer’s disease. Alzheimer Research Therapy 13, 51. 2021. Disponível em: https://alzres.biomedcentral.com/articles/10.1186/s13195-021-00783-x.
POWER, R. et al. Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial. Randomized Control Trials, 2022, volume 41, issue 2, p405-414. Disponível em: https://www.clinicalnutritionjournal.com/article/S0261-5614(21)00553-7/fulltext .
POZO, A.S.; GROWDON, J.H. Is Alzheimer's Disease Risk Modifiable?. Journal of Alzheimer’s Disease, 2019. Disponível em: https://pubmed.ncbi.nlm.nih.gov/30776012/.
SERENIKI, A.; VITAL, M.A.B. A doença de Alzheimer: aspectos fisiopatológicos e farmacológicos. Revista Psiquiatria Rio Grande do Sul. 2008. Disponível em: https://www.scielo.br/j/rprs/a/LNQzKPVKxLSsjbTnBCps4XM/?lang=pt&format=pdf .
WORLD HEALTH ORGANIZATION. World failing to address dementia challenge. 2021. Disponível em: https://www.who.int/news/item/02-09-2021-world-failing-to-address-dementia-challenge.
Downloads
Published
How to Cite
Issue
Section
Categories
License
Copyright (c) 2022 RECIMA21 - Revista Científica Multidisciplinar - ISSN 2675-6218
This work is licensed under a Creative Commons Attribution 4.0 International License.
Os direitos autorais dos artigos/resenhas/TCCs publicados pertecem à revista RECIMA21, e seguem o padrão Creative Commons (CC BY 4.0), permitindo a cópia ou reprodução, desde que cite a fonte e respeite os direitos dos autores e contenham menção aos mesmos nos créditos. Toda e qualquer obra publicada na revista, seu conteúdo é de responsabilidade dos autores, cabendo a RECIMA21 apenas ser o veículo de divulgação, seguindo os padrões nacionais e internacionais de publicação.